METHOD OF PREPARING SOLID DOSAGE FORMS COATED IN TWO LAYERS COMPRISING A WATER-INSOLUBLE POLYMER AND A WATER-SOLUBLE PORE FORMER
A method of preparing a coated solid dosage form is disclosed wherein a solid dosage form, such as a compressed tablet with active agent dispersed therein, is coated at least twice with a coating solution comprising a water-insoluble coating polymer and a water-soluble pore former, and cured after a...
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| creator | NOACK, ROBERT, M |
| description | A method of preparing a coated solid dosage form is disclosed wherein a solid dosage form, such as a compressed tablet with active agent dispersed therein, is coated at least twice with a coating solution comprising a water-insoluble coating polymer and a water-soluble pore former, and cured after at least the first coating step. The method of the present invention allows for the production of cured coated solid dosage forms using very short curing times. Coated solid dosage forms produced according to the present invention have been found to have long extended release characteristics.
Se describe un metodo para preparar una forma de dosificacion solida revestida, en donde una forma de dosificacion solida, tal como una tableta comprimida con agente activo disperso en la misma, es revestida por lo menos dos veces con una disolucion de revestimiento que comprende un polimero de revestimiento insoluble en agua y un agente formador de poros soluble en agua, y es curada despues de por lo menos la primera etapa de revesetimiento; el metodo de la presente invencion permite la produccion de lo formas de dosificacion solidas revestidas curadas utilizando tiempos de curacion muy cortos; se ha descubierto que las formas de dosificacion solidas revestidas, producidas segun la presente invencion, tienen caracteristicas de liberacion prolongada. |
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Se describe un metodo para preparar una forma de dosificacion solida revestida, en donde una forma de dosificacion solida, tal como una tableta comprimida con agente activo disperso en la misma, es revestida por lo menos dos veces con una disolucion de revestimiento que comprende un polimero de revestimiento insoluble en agua y un agente formador de poros soluble en agua, y es curada despues de por lo menos la primera etapa de revesetimiento; el metodo de la presente invencion permite la produccion de lo formas de dosificacion solidas revestidas curadas utilizando tiempos de curacion muy cortos; se ha descubierto que las formas de dosificacion solidas revestidas, producidas segun la presente invencion, tienen caracteristicas de liberacion prolongada.</description><edition>7</edition><language>eng ; spa</language><subject>APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL ; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPRAYING OR ATOMISING IN GENERAL ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050516&DB=EPODOC&CC=MX&NR=PA05001003A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050516&DB=EPODOC&CC=MX&NR=PA05001003A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NOACK, ROBERT, M</creatorcontrib><title>METHOD OF PREPARING SOLID DOSAGE FORMS COATED IN TWO LAYERS COMPRISING A WATER-INSOLUBLE POLYMER AND A WATER-SOLUBLE PORE FORMER</title><description>A method of preparing a coated solid dosage form is disclosed wherein a solid dosage form, such as a compressed tablet with active agent dispersed therein, is coated at least twice with a coating solution comprising a water-insoluble coating polymer and a water-soluble pore former, and cured after at least the first coating step. The method of the present invention allows for the production of cured coated solid dosage forms using very short curing times. Coated solid dosage forms produced according to the present invention have been found to have long extended release characteristics.
Se describe un metodo para preparar una forma de dosificacion solida revestida, en donde una forma de dosificacion solida, tal como una tableta comprimida con agente activo disperso en la misma, es revestida por lo menos dos veces con una disolucion de revestimiento que comprende un polimero de revestimiento insoluble en agua y un agente formador de poros soluble en agua, y es curada despues de por lo menos la primera etapa de revesetimiento; el metodo de la presente invencion permite la produccion de lo formas de dosificacion solidas revestidas curadas utilizando tiempos de curacion muy cortos; se ha descubierto que las formas de dosificacion solidas revestidas, producidas segun la presente invencion, tienen caracteristicas de liberacion prolongada.</description><subject>APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL</subject><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPRAYING OR ATOMISING IN GENERAL</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeodBveFSPEAsZm2gSQTJpXaVSkSV6KFegCPbouiW1cf_n_vL5OnxboiBVSAZ_SStSshkNEKFAVZIhTENkBOskYF2kHdEBjZIs-l9azDrEhoJoBT7Sb5eDAInkxrkUE69V1_G7-PkdfJ4tJfx7j55CrZFljnVRqHexfHoT_HW3x09uSl2AuxEyKT2V_QC9NiPMU</recordid><startdate>20050516</startdate><enddate>20050516</enddate><creator>NOACK, ROBERT, M</creator><scope>EVB</scope></search><sort><creationdate>20050516</creationdate><title>METHOD OF PREPARING SOLID DOSAGE FORMS COATED IN TWO LAYERS COMPRISING A WATER-INSOLUBLE POLYMER AND A WATER-SOLUBLE PORE FORMER</title><author>NOACK, ROBERT, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MXPA05001003A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2005</creationdate><topic>APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL</topic><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPRAYING OR ATOMISING IN GENERAL</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>NOACK, ROBERT, M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NOACK, ROBERT, M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF PREPARING SOLID DOSAGE FORMS COATED IN TWO LAYERS COMPRISING A WATER-INSOLUBLE POLYMER AND A WATER-SOLUBLE PORE FORMER</title><date>2005-05-16</date><risdate>2005</risdate><abstract>A method of preparing a coated solid dosage form is disclosed wherein a solid dosage form, such as a compressed tablet with active agent dispersed therein, is coated at least twice with a coating solution comprising a water-insoluble coating polymer and a water-soluble pore former, and cured after at least the first coating step. The method of the present invention allows for the production of cured coated solid dosage forms using very short curing times. Coated solid dosage forms produced according to the present invention have been found to have long extended release characteristics.
Se describe un metodo para preparar una forma de dosificacion solida revestida, en donde una forma de dosificacion solida, tal como una tableta comprimida con agente activo disperso en la misma, es revestida por lo menos dos veces con una disolucion de revestimiento que comprende un polimero de revestimiento insoluble en agua y un agente formador de poros soluble en agua, y es curada despues de por lo menos la primera etapa de revesetimiento; el metodo de la presente invencion permite la produccion de lo formas de dosificacion solidas revestidas curadas utilizando tiempos de curacion muy cortos; se ha descubierto que las formas de dosificacion solidas revestidas, producidas segun la presente invencion, tienen caracteristicas de liberacion prolongada.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPRAYING OR ATOMISING IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING |
| title | METHOD OF PREPARING SOLID DOSAGE FORMS COATED IN TWO LAYERS COMPRISING A WATER-INSOLUBLE POLYMER AND A WATER-SOLUBLE PORE FORMER |
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