RING FUSED PYRAZOLE DERIVATIVES
This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula (I) or (II): wherein Ar is optionally substituted aryl or heteroaryl, R1-R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers,...
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| creator | COUNDE O`YANG |
| description | This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula (I) or (II): wherein Ar is optionally substituted aryl or heteroaryl, R1-R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof. The invention further relates to processes for preparing such compounds, to pharmaceutical compositions containing such compounds, and to their use as therapeutic agents.
Esta invencion se refiere a compuestos que son generalmente antagonistas del receptor de CRF-1 y que estan representados por la formula I o II:(ver formula I, II)en donde Ar es heteroarilo o arilo opcionalmente sustituido, R1-R4 son como se definieron en la descripcion; o isomeros individuales, mezclas racemicas o no racemicas de isomeros, o sales farmaceuticamente aceptables de los mismos. La invencion se refiere ademas a procedimientos para preparar tales compuestos, a composiciones farmaceuticas que contienen tales compuestos, y a su uso como agentes terapeuticos. |
| format | Patent |
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Esta invencion se refiere a compuestos que son generalmente antagonistas del receptor de CRF-1 y que estan representados por la formula I o II:(ver formula I, II)en donde Ar es heteroarilo o arilo opcionalmente sustituido, R1-R4 son como se definieron en la descripcion; o isomeros individuales, mezclas racemicas o no racemicas de isomeros, o sales farmaceuticamente aceptables de los mismos. La invencion se refiere ademas a procedimientos para preparar tales compuestos, a composiciones farmaceuticas que contienen tales compuestos, y a su uso como agentes terapeuticos.</description><edition>7</edition><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20041011&DB=EPODOC&CC=MX&NR=PA04005426A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20041011&DB=EPODOC&CC=MX&NR=PA04005426A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>COUNDE O`YANG</creatorcontrib><title>RING FUSED PYRAZOLE DERIVATIVES</title><description>This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula (I) or (II): wherein Ar is optionally substituted aryl or heteroaryl, R1-R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof. The invention further relates to processes for preparing such compounds, to pharmaceutical compositions containing such compounds, and to their use as therapeutic agents.
Esta invencion se refiere a compuestos que son generalmente antagonistas del receptor de CRF-1 y que estan representados por la formula I o II:(ver formula I, II)en donde Ar es heteroarilo o arilo opcionalmente sustituido, R1-R4 son como se definieron en la descripcion; o isomeros individuales, mezclas racemicas o no racemicas de isomeros, o sales farmaceuticamente aceptables de los mismos. La invencion se refiere ademas a procedimientos para preparar tales compuestos, a composiciones farmaceuticas que contienen tales compuestos, y a su uso como agentes terapeuticos.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAP8vRzV3ALDXZ1UQiIDHKM8vdxVXBxDfIMcwzxDHMN5mFgTUvMKU7lhdLcDEpuriHOHrqpBfnxqcUFicmpeakl8b4RAY4GJgYGpiZGZo7GRCkCADJkIp8</recordid><startdate>20041011</startdate><enddate>20041011</enddate><creator>COUNDE O`YANG</creator><scope>EVB</scope></search><sort><creationdate>20041011</creationdate><title>RING FUSED PYRAZOLE DERIVATIVES</title><author>COUNDE O`YANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MXPA04005426A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2004</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>COUNDE O`YANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>COUNDE O`YANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RING FUSED PYRAZOLE DERIVATIVES</title><date>2004-10-11</date><risdate>2004</risdate><abstract>This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula (I) or (II): wherein Ar is optionally substituted aryl or heteroaryl, R1-R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof. The invention further relates to processes for preparing such compounds, to pharmaceutical compositions containing such compounds, and to their use as therapeutic agents.
Esta invencion se refiere a compuestos que son generalmente antagonistas del receptor de CRF-1 y que estan representados por la formula I o II:(ver formula I, II)en donde Ar es heteroarilo o arilo opcionalmente sustituido, R1-R4 son como se definieron en la descripcion; o isomeros individuales, mezclas racemicas o no racemicas de isomeros, o sales farmaceuticamente aceptables de los mismos. La invencion se refiere ademas a procedimientos para preparar tales compuestos, a composiciones farmaceuticas que contienen tales compuestos, y a su uso como agentes terapeuticos.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | RING FUSED PYRAZOLE DERIVATIVES |
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