METHOD AND APPARATUS FOR PREPARING PARTICLES

Method for Preparing a target substance in particulate form, comprising introducing into a particle formation vessel, through separate first and second fluid inlet means respectively, (a) a "target solution/suspension" of the substance in a fluid vehicle and (b) a compressed fluid anti-sol...

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1. Verfasser: SRINIVAS PALAKODATY
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description Method for Preparing a target substance in particulate form, comprising introducing into a particle formation vessel, through separate first and second fluid inlet means respectively, (a) a "target solution/suspension" of the substance in a fluid vehicle and (b) a compressed fluid anti-solvent, and allowing the anti-solvent to extract the vehicle so as to form particles of the substance, wherein the anti-solvent fluid has a sonic, near-sonic or supersonic velocity as it enters the vessel, and wherein the anti-solvent and the target solution/suspension enter the vessel at different locations and meet downstream (in the direction of anti-solvent flow) of the second fluid inlet means. Also provided is apparatus for use in such a method. Se describe un metodo para preparar una sustancia objetivo en forma de particulas, que comprende introducir a un recipiente de formacion de particulas, a traves de primeros y segundos medios de entrada de fluido separados, respectivamente, (a) una "solucion/suspension objetivo" de la sustancia en un vehiculo fluido y (b) un antisolvente de fluido comprimido y permitir que el antisolvente extraiga el vehiculo para formar particulas de la sustancia, en donde el fluido antisolvente tiene una velocidad sonica, casi sonica o supersonica a medida que entra al recipiente y en donde el antisolvente y la solucion/suspension objetivo entran al recipiente en diferentes sitios y se encuentran corriente abajo (en la direccion del flujo del antisolvente) de los segundos medios de entrada del fluido. Tambien se proporciona un aparato para uso en tal metodo.
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Also provided is apparatus for use in such a method. Se describe un metodo para preparar una sustancia objetivo en forma de particulas, que comprende introducir a un recipiente de formacion de particulas, a traves de primeros y segundos medios de entrada de fluido separados, respectivamente, (a) una "solucion/suspension objetivo" de la sustancia en un vehiculo fluido y (b) un antisolvente de fluido comprimido y permitir que el antisolvente extraiga el vehiculo para formar particulas de la sustancia, en donde el fluido antisolvente tiene una velocidad sonica, casi sonica o supersonica a medida que entra al recipiente y en donde el antisolvente y la solucion/suspension objetivo entran al recipiente en diferentes sitios y se encuentran corriente abajo (en la direccion del flujo del antisolvente) de los segundos medios de entrada del fluido. 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Also provided is apparatus for use in such a method. Se describe un metodo para preparar una sustancia objetivo en forma de particulas, que comprende introducir a un recipiente de formacion de particulas, a traves de primeros y segundos medios de entrada de fluido separados, respectivamente, (a) una "solucion/suspension objetivo" de la sustancia en un vehiculo fluido y (b) un antisolvente de fluido comprimido y permitir que el antisolvente extraiga el vehiculo para formar particulas de la sustancia, en donde el fluido antisolvente tiene una velocidad sonica, casi sonica o supersonica a medida que entra al recipiente y en donde el antisolvente y la solucion/suspension objetivo entran al recipiente en diferentes sitios y se encuentran corriente abajo (en la direccion del flujo del antisolvente) de los segundos medios de entrada del fluido. Tambien se proporciona un aparato para uso en tal metodo.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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language eng ; spa
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subjects BABY COMFORTERS
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES
DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY
DEVICES FOR RECEIVING SPITTLE
DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR RELEVANT APPARATUS
TRANSPORTING
title METHOD AND APPARATUS FOR PREPARING PARTICLES
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