A CELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF
Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 percent of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, pa...
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| creator | MICHEL H. KLEIN RAAFAT E.F. FAHIM GAIL E.D. JACKSON LESLIE BOUX LARRY U. L. TAN JOHN THIPPHAWONG JOHN R. VOSE ANDREW HERBERT LUIS BARRETO |
| description | Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 percent of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material.
Las vacunas acelulares de pertussis comprenden toxina purificada o toxoide de la misma, hemaglutinina filamentosa, pertactin y aglutinogeno fimbrial formulados para conferir proteccion a por lo menos 70% de los miembros de una poblacion en riesgo. Los aglutinogenos fimbriales pueden prepararse a partir de una capa Bordetella, particularmente la capa B. pertussi, mediante un procedimiento de varias etapas que implica: la extraccion de los aglutinogenos fimbriales a partir de la pasta celular y la concentracion y purificacion del material extraído. |
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Las vacunas acelulares de pertussis comprenden toxina purificada o toxoide de la misma, hemaglutinina filamentosa, pertactin y aglutinogeno fimbrial formulados para conferir proteccion a por lo menos 70% de los miembros de una poblacion en riesgo. Los aglutinogenos fimbriales pueden prepararse a partir de una capa Bordetella, particularmente la capa B. pertussi, mediante un procedimiento de varias etapas que implica: la extraccion de los aglutinogenos fimbriales a partir de la pasta celular y la concentracion y purificacion del material extraído.</description><edition>6</edition><language>eng ; spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980228&DB=EPODOC&CC=MX&NR=9708481A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980228&DB=EPODOC&CC=MX&NR=9708481A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MICHEL H. KLEIN</creatorcontrib><creatorcontrib>RAAFAT E.F. FAHIM</creatorcontrib><creatorcontrib>GAIL E.D. JACKSON</creatorcontrib><creatorcontrib>LESLIE BOUX</creatorcontrib><creatorcontrib>LARRY U. L. TAN</creatorcontrib><creatorcontrib>JOHN THIPPHAWONG</creatorcontrib><creatorcontrib>JOHN R. VOSE</creatorcontrib><creatorcontrib>ANDREW HERBERT</creatorcontrib><creatorcontrib>LUIS BARRETO</creatorcontrib><title>A CELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF</title><description>Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 percent of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material.
Las vacunas acelulares de pertussis comprenden toxina purificada o toxoide de la misma, hemaglutinina filamentosa, pertactin y aglutinogeno fimbrial formulados para conferir proteccion a por lo menos 70% de los miembros de una poblacion en riesgo. Los aglutinogenos fimbriales pueden prepararse a partir de una capa Bordetella, particularmente la capa B. pertussi, mediante un procedimiento de varias etapas que implica: la extraccion de los aglutinogenos fimbriales a partir de la pasta celular y la concentracion y purificacion del material extraído.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBwVHB29fEJ9XEMUghwDQoJDQ72DFYIc3R29vRzDVZw9HNR8HUN8fB3CVbwd1MICHINcAxyDPH091MI8XANcvV342FgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8b4RluYGFiYWho7GhFUAAAy6KhY</recordid><startdate>19980228</startdate><enddate>19980228</enddate><creator>MICHEL H. KLEIN</creator><creator>RAAFAT E.F. FAHIM</creator><creator>GAIL E.D. JACKSON</creator><creator>LESLIE BOUX</creator><creator>LARRY U. L. TAN</creator><creator>JOHN THIPPHAWONG</creator><creator>JOHN R. VOSE</creator><creator>ANDREW HERBERT</creator><creator>LUIS BARRETO</creator><scope>EVB</scope></search><sort><creationdate>19980228</creationdate><title>A CELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF</title><author>MICHEL H. KLEIN ; RAAFAT E.F. FAHIM ; GAIL E.D. JACKSON ; LESLIE BOUX ; LARRY U. L. TAN ; JOHN THIPPHAWONG ; JOHN R. VOSE ; ANDREW HERBERT ; LUIS BARRETO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX9708481A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>1998</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MICHEL H. KLEIN</creatorcontrib><creatorcontrib>RAAFAT E.F. FAHIM</creatorcontrib><creatorcontrib>GAIL E.D. JACKSON</creatorcontrib><creatorcontrib>LESLIE BOUX</creatorcontrib><creatorcontrib>LARRY U. L. TAN</creatorcontrib><creatorcontrib>JOHN THIPPHAWONG</creatorcontrib><creatorcontrib>JOHN R. VOSE</creatorcontrib><creatorcontrib>ANDREW HERBERT</creatorcontrib><creatorcontrib>LUIS BARRETO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MICHEL H. KLEIN</au><au>RAAFAT E.F. FAHIM</au><au>GAIL E.D. JACKSON</au><au>LESLIE BOUX</au><au>LARRY U. L. TAN</au><au>JOHN THIPPHAWONG</au><au>JOHN R. VOSE</au><au>ANDREW HERBERT</au><au>LUIS BARRETO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A CELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF</title><date>1998-02-28</date><risdate>1998</risdate><abstract>Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 percent of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material.
Las vacunas acelulares de pertussis comprenden toxina purificada o toxoide de la misma, hemaglutinina filamentosa, pertactin y aglutinogeno fimbrial formulados para conferir proteccion a por lo menos 70% de los miembros de una poblacion en riesgo. Los aglutinogenos fimbriales pueden prepararse a partir de una capa Bordetella, particularmente la capa B. pertussi, mediante un procedimiento de varias etapas que implica: la extraccion de los aglutinogenos fimbriales a partir de la pasta celular y la concentracion y purificacion del material extraído.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | A CELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF |
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