RESIN PARTICLE, MEDICAL MATERIAL AND PHARMACEUTICAL PREPARATION CONTAINING SAID RESIN PARTICLE
A resin particle is provided which comprises an ethylene vinyl alcohol copolymer and 5 to 90 percent by weight of cilostazol incorporated therein, and has a particle size of not greater than 2,000 'mu'm. The resin particle, upon being administered orally, allows the concentration of cilost...
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| creator | HIROAKI YAMAMOTO SHINSUKE NAKAGAWA KEIGO YAMADA RIKA HAMAMOTO YUZO KIMURA SEIICHIRO IGUCHI TOSHIO NAKAMURA MINORU YAMATO |
| description | A resin particle is provided which comprises an ethylene vinyl alcohol copolymer and 5 to 90 percent by weight of cilostazol incorporated therein, and has a particle size of not greater than 2,000 'mu'm. The resin particle, upon being administered orally, allows the concentration of cilostazol in blood to be kept constant over an extended period of time and, therefore, remarkably alleviates side effects such as pain and headache which may otherwise be caused by rapid release of cilostazol into a body.
Se provee una partícula de resina que comprende un copolímero de etileno y alcohol vinílico y de 5 a 90% en peso de cilostazol incorporado en el mismo, y tiene un tamaño de partícula no mayor de 2,000 æm; la partícula de resina, al ser administrada oralmente, permite que la concentracion de cilostazol en sangre se mantenga constante durante un periodo prolongado y por lo tanto alivia notablemente los efectos secundarios tales como cefalgia y fuerte malestar, que pueden ocasionarse de otra manera por la liberacion rápida de cilostazol en el cuerpo. |
| format | Patent |
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Se provee una partícula de resina que comprende un copolímero de etileno y alcohol vinílico y de 5 a 90% en peso de cilostazol incorporado en el mismo, y tiene un tamaño de partícula no mayor de 2,000 æm; la partícula de resina, al ser administrada oralmente, permite que la concentracion de cilostazol en sangre se mantenga constante durante un periodo prolongado y por lo tanto alivia notablemente los efectos secundarios tales como cefalgia y fuerte malestar, que pueden ocasionarse de otra manera por la liberacion rápida de cilostazol en el cuerpo.</description><edition>6</edition><language>eng ; spa</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19971031&DB=EPODOC&CC=MX&NR=9705185A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19971031&DB=EPODOC&CC=MX&NR=9705185A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HIROAKI YAMAMOTO</creatorcontrib><creatorcontrib>SHINSUKE NAKAGAWA</creatorcontrib><creatorcontrib>KEIGO YAMADA</creatorcontrib><creatorcontrib>RIKA HAMAMOTO</creatorcontrib><creatorcontrib>YUZO KIMURA</creatorcontrib><creatorcontrib>SEIICHIRO IGUCHI</creatorcontrib><creatorcontrib>TOSHIO NAKAMURA</creatorcontrib><creatorcontrib>MINORU YAMATO</creatorcontrib><title>RESIN PARTICLE, MEDICAL MATERIAL AND PHARMACEUTICAL PREPARATION CONTAINING SAID RESIN PARTICLE</title><description>A resin particle is provided which comprises an ethylene vinyl alcohol copolymer and 5 to 90 percent by weight of cilostazol incorporated therein, and has a particle size of not greater than 2,000 'mu'm. The resin particle, upon being administered orally, allows the concentration of cilostazol in blood to be kept constant over an extended period of time and, therefore, remarkably alleviates side effects such as pain and headache which may otherwise be caused by rapid release of cilostazol into a body.
Se provee una partícula de resina que comprende un copolímero de etileno y alcohol vinílico y de 5 a 90% en peso de cilostazol incorporado en el mismo, y tiene un tamaño de partícula no mayor de 2,000 æm; la partícula de resina, al ser administrada oralmente, permite que la concentracion de cilostazol en sangre se mantenga constante durante un periodo prolongado y por lo tanto alivia notablemente los efectos secundarios tales como cefalgia y fuerte malestar, que pueden ocasionarse de otra manera por la liberacion rápida de cilostazol en el cuerpo.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1997</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgLcg329FMIcAwK8XT2cdVR8HV18XR29FHwdQxxDfIEMhz9XBQCPByDfB2dXUNDwHIBQa5ADY4hnv5-Cs7-fiGOnn6efu4KwY6eLgqo5vEwsKYl5hSn8kJpbgZ5N9cQZw_d1IL8-NTigsTk1LzUknjfCEtzA1NDC1NHY8IqAEWTMik</recordid><startdate>19971031</startdate><enddate>19971031</enddate><creator>HIROAKI YAMAMOTO</creator><creator>SHINSUKE NAKAGAWA</creator><creator>KEIGO YAMADA</creator><creator>RIKA HAMAMOTO</creator><creator>YUZO KIMURA</creator><creator>SEIICHIRO IGUCHI</creator><creator>TOSHIO NAKAMURA</creator><creator>MINORU YAMATO</creator><scope>EVB</scope></search><sort><creationdate>19971031</creationdate><title>RESIN PARTICLE, MEDICAL MATERIAL AND PHARMACEUTICAL PREPARATION CONTAINING SAID RESIN PARTICLE</title><author>HIROAKI YAMAMOTO ; SHINSUKE NAKAGAWA ; KEIGO YAMADA ; RIKA HAMAMOTO ; YUZO KIMURA ; SEIICHIRO IGUCHI ; TOSHIO NAKAMURA ; MINORU YAMATO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX9705185A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>1997</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>HIROAKI YAMAMOTO</creatorcontrib><creatorcontrib>SHINSUKE NAKAGAWA</creatorcontrib><creatorcontrib>KEIGO YAMADA</creatorcontrib><creatorcontrib>RIKA HAMAMOTO</creatorcontrib><creatorcontrib>YUZO KIMURA</creatorcontrib><creatorcontrib>SEIICHIRO IGUCHI</creatorcontrib><creatorcontrib>TOSHIO NAKAMURA</creatorcontrib><creatorcontrib>MINORU YAMATO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HIROAKI YAMAMOTO</au><au>SHINSUKE NAKAGAWA</au><au>KEIGO YAMADA</au><au>RIKA HAMAMOTO</au><au>YUZO KIMURA</au><au>SEIICHIRO IGUCHI</au><au>TOSHIO NAKAMURA</au><au>MINORU YAMATO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>RESIN PARTICLE, MEDICAL MATERIAL AND PHARMACEUTICAL PREPARATION CONTAINING SAID RESIN PARTICLE</title><date>1997-10-31</date><risdate>1997</risdate><abstract>A resin particle is provided which comprises an ethylene vinyl alcohol copolymer and 5 to 90 percent by weight of cilostazol incorporated therein, and has a particle size of not greater than 2,000 'mu'm. The resin particle, upon being administered orally, allows the concentration of cilostazol in blood to be kept constant over an extended period of time and, therefore, remarkably alleviates side effects such as pain and headache which may otherwise be caused by rapid release of cilostazol into a body.
Se provee una partícula de resina que comprende un copolímero de etileno y alcohol vinílico y de 5 a 90% en peso de cilostazol incorporado en el mismo, y tiene un tamaño de partícula no mayor de 2,000 æm; la partícula de resina, al ser administrada oralmente, permite que la concentracion de cilostazol en sangre se mantenga constante durante un periodo prolongado y por lo tanto alivia notablemente los efectos secundarios tales como cefalgia y fuerte malestar, que pueden ocasionarse de otra manera por la liberacion rápida de cilostazol en el cuerpo.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | RESIN PARTICLE, MEDICAL MATERIAL AND PHARMACEUTICAL PREPARATION CONTAINING SAID RESIN PARTICLE |
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