MULTI-POLYMER COMPOSITIONS FOR TRANSDERMAL DRUG DELIVERY

Multi-polymer compositions for the transdermal delivery of drugs, such as amine-functional drugs, in a flexible, finite form are described. The compositions comprise a polymer matrix that includes a drug or a pharmaceutically acceptable salt thereof and a polymer matrix comprising acrylic polymer(s)...

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Hauptverfasser: Joshua KULAKOFSKY, Puchun LIU
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creator Joshua KULAKOFSKY
Puchun LIU
description Multi-polymer compositions for the transdermal delivery of drugs, such as amine-functional drugs, in a flexible, finite form are described. The compositions comprise a polymer matrix that includes a drug or a pharmaceutically acceptable salt thereof and a polymer matrix comprising acrylic polymer(s), polyisobutylene polymer(s) and styrene-isoprene-styrene block copolymer(s). Methods of manufacturing and methods of using the compositions also are described. Se describen composiciones multipolimericas para la liberación transdermica de fármacos, tal como fármacos amino funcionales, en una forma flexible finita. Las composiciones comprenden una matriz polimerica que incluye un fármaco o una sal farmacéuticamente aceptable del mismo y una matriz polimerica que comprende polímeros acrílicos, polímeros de poliisobutileno y copolimeros en bloque de estireno - isopreno - estereno. También se describen métodos de elaboración y métodos para usar las composiciones.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title MULTI-POLYMER COMPOSITIONS FOR TRANSDERMAL DRUG DELIVERY
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