HUMAN ANTIBODIES AGAINST HUMAN TISSUE FACTOR
Isolated human monoclonal antibodies which bind to human TF and related antibody- based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies. La presente invención se refie...
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| creator | TOM VINK MAROESKA OUDSHOORN DAVID P.E. SATIJN SANDRA VERPLOEGEN PAUL PARREN VIBEKE MILLER BREINHOLT ROB N. DE JONG OLE BAADSGAARD WILLEM KAREL BLEEKER EVA EHRNROOTH RENE M.A. HOET MISCHA HOUTKAMP JAN VAN DE WINKEL |
| description | Isolated human monoclonal antibodies which bind to human TF and related antibody- based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
La presente invención se refiere a un anticuerpo humano el cual une factor tisular (TF), caracterizado porque: compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la SEC ID NO: 9 y una región VL que comprende la secuencia de las SEC ID NO: 65, y no compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la secuencia de la SEC ID NO: 37 y una región VL que comprende la secuencia de la SEC ID NO: 93. |
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La presente invención se refiere a un anticuerpo humano el cual une factor tisular (TF), caracterizado porque: compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la SEC ID NO: 9 y una región VL que comprende la secuencia de las SEC ID NO: 65, y no compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la secuencia de la SEC ID NO: 37 y una región VL que comprende la secuencia de la SEC ID NO: 93.</description><language>eng ; spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160429&DB=EPODOC&CC=MX&NR=338754B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160429&DB=EPODOC&CC=MX&NR=338754B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TOM VINK</creatorcontrib><creatorcontrib>MAROESKA OUDSHOORN</creatorcontrib><creatorcontrib>DAVID P.E. SATIJN</creatorcontrib><creatorcontrib>SANDRA VERPLOEGEN</creatorcontrib><creatorcontrib>PAUL PARREN</creatorcontrib><creatorcontrib>VIBEKE MILLER BREINHOLT</creatorcontrib><creatorcontrib>ROB N. DE JONG</creatorcontrib><creatorcontrib>OLE BAADSGAARD</creatorcontrib><creatorcontrib>WILLEM KAREL BLEEKER</creatorcontrib><creatorcontrib>EVA EHRNROOTH</creatorcontrib><creatorcontrib>RENE M.A. HOET</creatorcontrib><creatorcontrib>MISCHA HOUTKAMP</creatorcontrib><creatorcontrib>JAN VAN DE WINKEL</creatorcontrib><title>HUMAN ANTIBODIES AGAINST HUMAN TISSUE FACTOR</title><description>Isolated human monoclonal antibodies which bind to human TF and related antibody- based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
La presente invención se refiere a un anticuerpo humano el cual une factor tisular (TF), caracterizado porque: compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la SEC ID NO: 9 y una región VL que comprende la secuencia de las SEC ID NO: 65, y no compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la secuencia de la SEC ID NO: 37 y una región VL que comprende la secuencia de la SEC ID NO: 93.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDxCPV19FNw9AvxdPJ38XQNVnB0d_T0Cw5RgEiEeAYHh7oquDk6h_gH8TCwpiXmFKfyQmluBjk31xBnD93Ugvz41OKCxOTUvNSSeN8IY2MLc1MTJ2OCCgDIUCQq</recordid><startdate>20160429</startdate><enddate>20160429</enddate><creator>TOM VINK</creator><creator>MAROESKA OUDSHOORN</creator><creator>DAVID P.E. SATIJN</creator><creator>SANDRA VERPLOEGEN</creator><creator>PAUL PARREN</creator><creator>VIBEKE MILLER BREINHOLT</creator><creator>ROB N. DE JONG</creator><creator>OLE BAADSGAARD</creator><creator>WILLEM KAREL BLEEKER</creator><creator>EVA EHRNROOTH</creator><creator>RENE M.A. HOET</creator><creator>MISCHA HOUTKAMP</creator><creator>JAN VAN DE WINKEL</creator><scope>EVB</scope></search><sort><creationdate>20160429</creationdate><title>HUMAN ANTIBODIES AGAINST HUMAN TISSUE FACTOR</title><author>TOM VINK ; MAROESKA OUDSHOORN ; DAVID P.E. SATIJN ; SANDRA VERPLOEGEN ; PAUL PARREN ; VIBEKE MILLER BREINHOLT ; ROB N. DE JONG ; OLE BAADSGAARD ; WILLEM KAREL BLEEKER ; EVA EHRNROOTH ; RENE M.A. HOET ; MISCHA HOUTKAMP ; JAN VAN DE WINKEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX338754B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TOM VINK</creatorcontrib><creatorcontrib>MAROESKA OUDSHOORN</creatorcontrib><creatorcontrib>DAVID P.E. SATIJN</creatorcontrib><creatorcontrib>SANDRA VERPLOEGEN</creatorcontrib><creatorcontrib>PAUL PARREN</creatorcontrib><creatorcontrib>VIBEKE MILLER BREINHOLT</creatorcontrib><creatorcontrib>ROB N. DE JONG</creatorcontrib><creatorcontrib>OLE BAADSGAARD</creatorcontrib><creatorcontrib>WILLEM KAREL BLEEKER</creatorcontrib><creatorcontrib>EVA EHRNROOTH</creatorcontrib><creatorcontrib>RENE M.A. HOET</creatorcontrib><creatorcontrib>MISCHA HOUTKAMP</creatorcontrib><creatorcontrib>JAN VAN DE WINKEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TOM VINK</au><au>MAROESKA OUDSHOORN</au><au>DAVID P.E. SATIJN</au><au>SANDRA VERPLOEGEN</au><au>PAUL PARREN</au><au>VIBEKE MILLER BREINHOLT</au><au>ROB N. DE JONG</au><au>OLE BAADSGAARD</au><au>WILLEM KAREL BLEEKER</au><au>EVA EHRNROOTH</au><au>RENE M.A. HOET</au><au>MISCHA HOUTKAMP</au><au>JAN VAN DE WINKEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HUMAN ANTIBODIES AGAINST HUMAN TISSUE FACTOR</title><date>2016-04-29</date><risdate>2016</risdate><abstract>Isolated human monoclonal antibodies which bind to human TF and related antibody- based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
La presente invención se refiere a un anticuerpo humano el cual une factor tisular (TF), caracterizado porque: compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la SEC ID NO: 9 y una región VL que comprende la secuencia de las SEC ID NO: 65, y no compite por unión de TF con un anticuerpo de referencia que comprende una región VH que comprende la secuencia de la SEC ID NO: 37 y una región VL que comprende la secuencia de la SEC ID NO: 93.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HUMAN ANTIBODIES AGAINST HUMAN TISSUE FACTOR |
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