HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE AS PROTEIN KINASE INHIBITORS
Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological condit...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | eng ; spa |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | JASON SIMON PARNES PATRICK WILLIAM PAPA SOPHIE PERRIN-NINKOVIC DEHUA HUANG MARIA MERCEDES MEDEROS DELGADO LIDA RADNIA TEHRANI BRANDEN G. LEE DEBORAH SUE MORTENSEN GARRICK K. PACKARD RONALD J. ALBERS JOHN JOSEPH SAPIENZA ROY LEONARD HARRIS III GRAZIELLA ISABEL SHEVLIN KIMBERLY LYN SCHWARZ |
description | Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
Se proporcionan aquí los compuestos heterocíclicos que tienen la siguiente estructura: (I) en donde R1, R2, L, X, Y, Z, Q, A y B son como se definen aquí, las composiciones que comprenden una cantidad efectiva de un compuesto de heteroarilo y métodos para el tratamiento o prevención del cáncer, condiciones inflamatorias, condiciones inmunológicas, condiciones metabólicas y condiciones tratables o prevenibles por inhibición de una vía o trayectoria de la cinasa, que comprende la administración de una cantidad efectiva de un compuesto de heteroarilo a un paciente en necesidad del mismo.(ver fórmula (I)). |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MX337906B</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MX337906B</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MX337906B3</originalsourceid><addsrcrecordid>eNrjZAjzcA1xDfJ3DIr0UXD29w3wD_VzCdaBMIM9Qzz9_YIVQjxcg1z93XQUHP1cQBzPIIXQYFcFx2CFgCD_EFdPPwVvTz9HoIinn4enk2eIf1AwDwNrWmJOcSovlOZmkHNzDXH20E0tyI9PLS5ITE7NSy2J940wNja3NDBzMiaoAACf2y_j</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE AS PROTEIN KINASE INHIBITORS</title><source>esp@cenet</source><creator>JASON SIMON PARNES ; PATRICK WILLIAM PAPA ; SOPHIE PERRIN-NINKOVIC ; DEHUA HUANG ; MARIA MERCEDES MEDEROS DELGADO ; LIDA RADNIA TEHRANI ; BRANDEN G. LEE ; DEBORAH SUE MORTENSEN ; GARRICK K. PACKARD ; RONALD J. ALBERS ; JOHN JOSEPH SAPIENZA ; ROY LEONARD HARRIS III ; GRAZIELLA ISABEL SHEVLIN ; KIMBERLY LYN SCHWARZ</creator><creatorcontrib>JASON SIMON PARNES ; PATRICK WILLIAM PAPA ; SOPHIE PERRIN-NINKOVIC ; DEHUA HUANG ; MARIA MERCEDES MEDEROS DELGADO ; LIDA RADNIA TEHRANI ; BRANDEN G. LEE ; DEBORAH SUE MORTENSEN ; GARRICK K. PACKARD ; RONALD J. ALBERS ; JOHN JOSEPH SAPIENZA ; ROY LEONARD HARRIS III ; GRAZIELLA ISABEL SHEVLIN ; KIMBERLY LYN SCHWARZ</creatorcontrib><description>Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
Se proporcionan aquí los compuestos heterocíclicos que tienen la siguiente estructura: (I) en donde R1, R2, L, X, Y, Z, Q, A y B son como se definen aquí, las composiciones que comprenden una cantidad efectiva de un compuesto de heteroarilo y métodos para el tratamiento o prevención del cáncer, condiciones inflamatorias, condiciones inmunológicas, condiciones metabólicas y condiciones tratables o prevenibles por inhibición de una vía o trayectoria de la cinasa, que comprende la administración de una cantidad efectiva de un compuesto de heteroarilo a un paciente en necesidad del mismo.(ver fórmula (I)).</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160328&DB=EPODOC&CC=MX&NR=337906B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160328&DB=EPODOC&CC=MX&NR=337906B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JASON SIMON PARNES</creatorcontrib><creatorcontrib>PATRICK WILLIAM PAPA</creatorcontrib><creatorcontrib>SOPHIE PERRIN-NINKOVIC</creatorcontrib><creatorcontrib>DEHUA HUANG</creatorcontrib><creatorcontrib>MARIA MERCEDES MEDEROS DELGADO</creatorcontrib><creatorcontrib>LIDA RADNIA TEHRANI</creatorcontrib><creatorcontrib>BRANDEN G. LEE</creatorcontrib><creatorcontrib>DEBORAH SUE MORTENSEN</creatorcontrib><creatorcontrib>GARRICK K. PACKARD</creatorcontrib><creatorcontrib>RONALD J. ALBERS</creatorcontrib><creatorcontrib>JOHN JOSEPH SAPIENZA</creatorcontrib><creatorcontrib>ROY LEONARD HARRIS III</creatorcontrib><creatorcontrib>GRAZIELLA ISABEL SHEVLIN</creatorcontrib><creatorcontrib>KIMBERLY LYN SCHWARZ</creatorcontrib><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE AS PROTEIN KINASE INHIBITORS</title><description>Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
Se proporcionan aquí los compuestos heterocíclicos que tienen la siguiente estructura: (I) en donde R1, R2, L, X, Y, Z, Q, A y B son como se definen aquí, las composiciones que comprenden una cantidad efectiva de un compuesto de heteroarilo y métodos para el tratamiento o prevención del cáncer, condiciones inflamatorias, condiciones inmunológicas, condiciones metabólicas y condiciones tratables o prevenibles por inhibición de una vía o trayectoria de la cinasa, que comprende la administración de una cantidad efectiva de un compuesto de heteroarilo a un paciente en necesidad del mismo.(ver fórmula (I)).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAjzcA1xDfJ3DIr0UXD29w3wD_VzCdaBMIM9Qzz9_YIVQjxcg1z93XQUHP1cQBzPIIXQYFcFx2CFgCD_EFdPPwVvTz9HoIinn4enk2eIf1AwDwNrWmJOcSovlOZmkHNzDXH20E0tyI9PLS5ITE7NSy2J940wNja3NDBzMiaoAACf2y_j</recordid><startdate>20160328</startdate><enddate>20160328</enddate><creator>JASON SIMON PARNES</creator><creator>PATRICK WILLIAM PAPA</creator><creator>SOPHIE PERRIN-NINKOVIC</creator><creator>DEHUA HUANG</creator><creator>MARIA MERCEDES MEDEROS DELGADO</creator><creator>LIDA RADNIA TEHRANI</creator><creator>BRANDEN G. LEE</creator><creator>DEBORAH SUE MORTENSEN</creator><creator>GARRICK K. PACKARD</creator><creator>RONALD J. ALBERS</creator><creator>JOHN JOSEPH SAPIENZA</creator><creator>ROY LEONARD HARRIS III</creator><creator>GRAZIELLA ISABEL SHEVLIN</creator><creator>KIMBERLY LYN SCHWARZ</creator><scope>EVB</scope></search><sort><creationdate>20160328</creationdate><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE AS PROTEIN KINASE INHIBITORS</title><author>JASON SIMON PARNES ; PATRICK WILLIAM PAPA ; SOPHIE PERRIN-NINKOVIC ; DEHUA HUANG ; MARIA MERCEDES MEDEROS DELGADO ; LIDA RADNIA TEHRANI ; BRANDEN G. LEE ; DEBORAH SUE MORTENSEN ; GARRICK K. PACKARD ; RONALD J. ALBERS ; JOHN JOSEPH SAPIENZA ; ROY LEONARD HARRIS III ; GRAZIELLA ISABEL SHEVLIN ; KIMBERLY LYN SCHWARZ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX337906B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>JASON SIMON PARNES</creatorcontrib><creatorcontrib>PATRICK WILLIAM PAPA</creatorcontrib><creatorcontrib>SOPHIE PERRIN-NINKOVIC</creatorcontrib><creatorcontrib>DEHUA HUANG</creatorcontrib><creatorcontrib>MARIA MERCEDES MEDEROS DELGADO</creatorcontrib><creatorcontrib>LIDA RADNIA TEHRANI</creatorcontrib><creatorcontrib>BRANDEN G. LEE</creatorcontrib><creatorcontrib>DEBORAH SUE MORTENSEN</creatorcontrib><creatorcontrib>GARRICK K. PACKARD</creatorcontrib><creatorcontrib>RONALD J. ALBERS</creatorcontrib><creatorcontrib>JOHN JOSEPH SAPIENZA</creatorcontrib><creatorcontrib>ROY LEONARD HARRIS III</creatorcontrib><creatorcontrib>GRAZIELLA ISABEL SHEVLIN</creatorcontrib><creatorcontrib>KIMBERLY LYN SCHWARZ</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JASON SIMON PARNES</au><au>PATRICK WILLIAM PAPA</au><au>SOPHIE PERRIN-NINKOVIC</au><au>DEHUA HUANG</au><au>MARIA MERCEDES MEDEROS DELGADO</au><au>LIDA RADNIA TEHRANI</au><au>BRANDEN G. LEE</au><au>DEBORAH SUE MORTENSEN</au><au>GARRICK K. PACKARD</au><au>RONALD J. ALBERS</au><au>JOHN JOSEPH SAPIENZA</au><au>ROY LEONARD HARRIS III</au><au>GRAZIELLA ISABEL SHEVLIN</au><au>KIMBERLY LYN SCHWARZ</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE AS PROTEIN KINASE INHIBITORS</title><date>2016-03-28</date><risdate>2016</risdate><abstract>Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
Se proporcionan aquí los compuestos heterocíclicos que tienen la siguiente estructura: (I) en donde R1, R2, L, X, Y, Z, Q, A y B son como se definen aquí, las composiciones que comprenden una cantidad efectiva de un compuesto de heteroarilo y métodos para el tratamiento o prevención del cáncer, condiciones inflamatorias, condiciones inmunológicas, condiciones metabólicas y condiciones tratables o prevenibles por inhibición de una vía o trayectoria de la cinasa, que comprende la administración de una cantidad efectiva de un compuesto de heteroarilo a un paciente en necesidad del mismo.(ver fórmula (I)).</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng ; spa |
recordid | cdi_epo_espacenet_MX337906B |
source | esp@cenet |
subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE AS PROTEIN KINASE INHIBITORS |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T03%3A29%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JASON%20SIMON%20PARNES&rft.date=2016-03-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMX337906B%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |