TREATMENT OF LUNG CONDITIONS WITH INTEGRIN SUBUNIT ALPHA 1 (ITGA1) INHIBITORS

The present disclosure provides methods of treating subjects having a lung disease such as a fibrotic lung disease, pulmonary fibrosis, interstitial lung disease, chronic obstructive pulmonary disease (COPD), or asthma, or at risk of developing a lung disease, and methods of identifying subjects hav...

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Bibliographische Detailangaben
Hauptverfasser: BARAS Aris, FERREIRA Manuel Allen Revez, ABECASIS Goncalo, HOROWITZ Julie, E, SIMINOVITCH Katherine, SUCIU Maria Cristina
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present disclosure provides methods of treating subjects having a lung disease such as a fibrotic lung disease, pulmonary fibrosis, interstitial lung disease, chronic obstructive pulmonary disease (COPD), or asthma, or at risk of developing a lung disease, and methods of identifying subjects having an increased risk of developing a lung disease. La presente descripción proporciona métodos para el tratamiento de sujetos que tienen una enfermedad pulmonar, tal como una enfermedad pulmonar fibrótica, fibrosis pulmonar, enfermedad pulmonar intersticial, enfermedad pulmonar obstructiva crónica (EPOC) o asma, o se encuentra en riesgo de desarrollar una enfermedad pulmonar, y métodos para identificar sujetos que tienen un mayor riesgo de desarrollar una enfermedad pulmonar.