ANTI-MUTANT CALRETICULIN (CALR) ANTIBODIES AND USES THEREOF

Anti-mutant calreticulin (mutCALR) antibodies are disclosed. Also disclosed are related nucleic acids, vectors, cells, kits, and pharmaceutical compositions. Methods of treating or diagnosing myeloproliferative neoplasms with the anti-mutCALR antibodies are also disclosed. Se describen anticuerpos a...

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Bibliographische Detailangaben
Hauptverfasser:	BUONPANE Rebecca A, DELLER Marc C, STEWART Shaun M, MAYES Patrick, NASTRI Horacio G, WASS Brittney Melissa, REIS Edimara S, ZHOU Jing, CELIK Hamza, ZHAO Yonghong, LEI Hsiang-ting, MCQUIRTER Leslie Brooke Epling
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	Anti-mutant calreticulin (mutCALR) antibodies are disclosed. Also disclosed are related nucleic acids, vectors, cells, kits, and pharmaceutical compositions. Methods of treating or diagnosing myeloproliferative neoplasms with the anti-mutCALR antibodies are also disclosed. Se describen anticuerpos anti calreticulina mutante (mutCALR). También se describen ácidos nucleicos, vectores, células, kits y composiciones farmacéuticas relacionadas. También se describen métodos para tratar o diagnosticar neoplasias mieloproliferativas con los anticuerpos anti-mutCALR.