MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER

The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. La presente invención se refiere a terapia de combinación usando un agente...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	BREIJ Esther Cornelia Wilhelmina, GUELEN Lars, BAJAJ Gaurav, NEIJSSEN Jost, KUZMANOV Ivan, MUIK Alexander, HIBBERT Richard, FELLERMEIER-KOPF Sina, PAULMANN Claudia, III ADAMS Homer, LABRIJN Aran Frank, SAHIN Ugur, FU Yali, GIESEKE Friederike, NIEWOOD Michelle, SCHUURMAN Janine, BECKMANN Karsten, HIGGS Brandon, DE KREUK Bart - Jan, GARRIDO CASTRO Patricia, FERESHTEH Mark, SPIRES Vanessa, BLUM Jordan
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	BREIJ Esther Cornelia Wilhelmina GUELEN Lars BAJAJ Gaurav NEIJSSEN Jost KUZMANOV Ivan MUIK Alexander HIBBERT Richard FELLERMEIER-KOPF Sina PAULMANN Claudia III ADAMS Homer LABRIJN Aran Frank SAHIN Ugur FU Yali GIESEKE Friederike NIEWOOD Michelle SCHUURMAN Janine BECKMANN Karsten HIGGS Brandon DE KREUK Bart - Jan GARRIDO CASTRO Patricia FERESHTEH Mark SPIRES Vanessa BLUM Jordan
description	The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. La presente invención se refiere a terapia de combinación usando un agente de unión que se une a CD40 humano y a CD137 humano en combinación con un inhibidor de punto de control para reducir o prevenir la progresión de un tumor o tratar cáncer.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MX2024000674A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MX2024000674A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MX2024000674A3</originalsourceid><addsrcrecordid>eNqNyrEKwjAQgOEsDqK-w-EuxDbY-bwm7YG9lDQFnUqROIkW6vtjBx_A6fuHf636pr9E7lpL7JjgzFKyVICVldgtIEsXgUqjAaVc4pgXwALkm-XFyF4g1jZgewPnAxAK2bBVq8f4nNPu50btnY1UH9L0HtI8jff0Sp-huWY6M1rrU2Ew_2v6AlZ9MAc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER</title><source>esp@cenet</source><creator>BREIJ Esther Cornelia Wilhelmina ; GUELEN Lars ; BAJAJ Gaurav ; NEIJSSEN Jost ; KUZMANOV Ivan ; MUIK Alexander ; HIBBERT Richard ; FELLERMEIER-KOPF Sina ; PAULMANN Claudia ; III ADAMS Homer ; LABRIJN Aran Frank ; SAHIN Ugur ; FU Yali ; GIESEKE Friederike ; NIEWOOD Michelle ; SCHUURMAN Janine ; BECKMANN Karsten ; HIGGS Brandon ; DE KREUK Bart - Jan ; GARRIDO CASTRO Patricia ; FERESHTEH Mark ; SPIRES Vanessa ; BLUM Jordan</creator><creatorcontrib>BREIJ Esther Cornelia Wilhelmina ; GUELEN Lars ; BAJAJ Gaurav ; NEIJSSEN Jost ; KUZMANOV Ivan ; MUIK Alexander ; HIBBERT Richard ; FELLERMEIER-KOPF Sina ; PAULMANN Claudia ; III ADAMS Homer ; LABRIJN Aran Frank ; SAHIN Ugur ; FU Yali ; GIESEKE Friederike ; NIEWOOD Michelle ; SCHUURMAN Janine ; BECKMANN Karsten ; HIGGS Brandon ; DE KREUK Bart - Jan ; GARRIDO CASTRO Patricia ; FERESHTEH Mark ; SPIRES Vanessa ; BLUM Jordan</creatorcontrib><description>The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. La presente invención se refiere a terapia de combinación usando un agente de unión que se une a CD40 humano y a CD137 humano en combinación con un inhibidor de punto de control para reducir o prevenir la progresión de un tumor o tratar cáncer.</description><language>eng ; spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240207&DB=EPODOC&CC=MX&NR=2024000674A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240207&DB=EPODOC&CC=MX&NR=2024000674A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BREIJ Esther Cornelia Wilhelmina</creatorcontrib><creatorcontrib>GUELEN Lars</creatorcontrib><creatorcontrib>BAJAJ Gaurav</creatorcontrib><creatorcontrib>NEIJSSEN Jost</creatorcontrib><creatorcontrib>KUZMANOV Ivan</creatorcontrib><creatorcontrib>MUIK Alexander</creatorcontrib><creatorcontrib>HIBBERT Richard</creatorcontrib><creatorcontrib>FELLERMEIER-KOPF Sina</creatorcontrib><creatorcontrib>PAULMANN Claudia</creatorcontrib><creatorcontrib>III ADAMS Homer</creatorcontrib><creatorcontrib>LABRIJN Aran Frank</creatorcontrib><creatorcontrib>SAHIN Ugur</creatorcontrib><creatorcontrib>FU Yali</creatorcontrib><creatorcontrib>GIESEKE Friederike</creatorcontrib><creatorcontrib>NIEWOOD Michelle</creatorcontrib><creatorcontrib>SCHUURMAN Janine</creatorcontrib><creatorcontrib>BECKMANN Karsten</creatorcontrib><creatorcontrib>HIGGS Brandon</creatorcontrib><creatorcontrib>DE KREUK Bart - Jan</creatorcontrib><creatorcontrib>GARRIDO CASTRO Patricia</creatorcontrib><creatorcontrib>FERESHTEH Mark</creatorcontrib><creatorcontrib>SPIRES Vanessa</creatorcontrib><creatorcontrib>BLUM Jordan</creatorcontrib><title>MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER</title><description>The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. La presente invención se refiere a terapia de combinación usando un agente de unión que se une a CD40 humano y a CD137 humano en combinación con un inhibidor de punto de control para reducir o prevenir la progresión de un tumor o tratar cáncer.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEsDqK-w-EuxDbY-bwm7YG9lDQFnUqROIkW6vtjBx_A6fuHf636pr9E7lpL7JjgzFKyVICVldgtIEsXgUqjAaVc4pgXwALkm-XFyF4g1jZgewPnAxAK2bBVq8f4nNPu50btnY1UH9L0HtI8jff0Sp-huWY6M1rrU2Ew_2v6AlZ9MAc</recordid><startdate>20240207</startdate><enddate>20240207</enddate><creator>BREIJ Esther Cornelia Wilhelmina</creator><creator>GUELEN Lars</creator><creator>BAJAJ Gaurav</creator><creator>NEIJSSEN Jost</creator><creator>KUZMANOV Ivan</creator><creator>MUIK Alexander</creator><creator>HIBBERT Richard</creator><creator>FELLERMEIER-KOPF Sina</creator><creator>PAULMANN Claudia</creator><creator>III ADAMS Homer</creator><creator>LABRIJN Aran Frank</creator><creator>SAHIN Ugur</creator><creator>FU Yali</creator><creator>GIESEKE Friederike</creator><creator>NIEWOOD Michelle</creator><creator>SCHUURMAN Janine</creator><creator>BECKMANN Karsten</creator><creator>HIGGS Brandon</creator><creator>DE KREUK Bart - Jan</creator><creator>GARRIDO CASTRO Patricia</creator><creator>FERESHTEH Mark</creator><creator>SPIRES Vanessa</creator><creator>BLUM Jordan</creator><scope>EVB</scope></search><sort><creationdate>20240207</creationdate><title>MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER</title><author>BREIJ Esther Cornelia Wilhelmina ; GUELEN Lars ; BAJAJ Gaurav ; NEIJSSEN Jost ; KUZMANOV Ivan ; MUIK Alexander ; HIBBERT Richard ; FELLERMEIER-KOPF Sina ; PAULMANN Claudia ; III ADAMS Homer ; LABRIJN Aran Frank ; SAHIN Ugur ; FU Yali ; GIESEKE Friederike ; NIEWOOD Michelle ; SCHUURMAN Janine ; BECKMANN Karsten ; HIGGS Brandon ; DE KREUK Bart - Jan ; GARRIDO CASTRO Patricia ; FERESHTEH Mark ; SPIRES Vanessa ; BLUM Jordan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2024000674A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BREIJ Esther Cornelia Wilhelmina</creatorcontrib><creatorcontrib>GUELEN Lars</creatorcontrib><creatorcontrib>BAJAJ Gaurav</creatorcontrib><creatorcontrib>NEIJSSEN Jost</creatorcontrib><creatorcontrib>KUZMANOV Ivan</creatorcontrib><creatorcontrib>MUIK Alexander</creatorcontrib><creatorcontrib>HIBBERT Richard</creatorcontrib><creatorcontrib>FELLERMEIER-KOPF Sina</creatorcontrib><creatorcontrib>PAULMANN Claudia</creatorcontrib><creatorcontrib>III ADAMS Homer</creatorcontrib><creatorcontrib>LABRIJN Aran Frank</creatorcontrib><creatorcontrib>SAHIN Ugur</creatorcontrib><creatorcontrib>FU Yali</creatorcontrib><creatorcontrib>GIESEKE Friederike</creatorcontrib><creatorcontrib>NIEWOOD Michelle</creatorcontrib><creatorcontrib>SCHUURMAN Janine</creatorcontrib><creatorcontrib>BECKMANN Karsten</creatorcontrib><creatorcontrib>HIGGS Brandon</creatorcontrib><creatorcontrib>DE KREUK Bart - Jan</creatorcontrib><creatorcontrib>GARRIDO CASTRO Patricia</creatorcontrib><creatorcontrib>FERESHTEH Mark</creatorcontrib><creatorcontrib>SPIRES Vanessa</creatorcontrib><creatorcontrib>BLUM Jordan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BREIJ Esther Cornelia Wilhelmina</au><au>GUELEN Lars</au><au>BAJAJ Gaurav</au><au>NEIJSSEN Jost</au><au>KUZMANOV Ivan</au><au>MUIK Alexander</au><au>HIBBERT Richard</au><au>FELLERMEIER-KOPF Sina</au><au>PAULMANN Claudia</au><au>III ADAMS Homer</au><au>LABRIJN Aran Frank</au><au>SAHIN Ugur</au><au>FU Yali</au><au>GIESEKE Friederike</au><au>NIEWOOD Michelle</au><au>SCHUURMAN Janine</au><au>BECKMANN Karsten</au><au>HIGGS Brandon</au><au>DE KREUK Bart - Jan</au><au>GARRIDO CASTRO Patricia</au><au>FERESHTEH Mark</au><au>SPIRES Vanessa</au><au>BLUM Jordan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER</title><date>2024-02-07</date><risdate>2024</risdate><abstract>The present invention relates to combination therapy using a binding agent that binds to human CD40 and to human CD137 in combination with a checkpoint inhibitor to reduce or prevent progression of a tumor or treating cancer. La presente invención se refiere a terapia de combinación usando un agente de unión que se une a CD40 humano y a CD137 humano en combinación con un inhibidor de punto de control para reducir o prevenir la progresión de un tumor o tratar cáncer.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng ; spa
recordid	cdi_epo_espacenet_MX2024000674A
source	esp@cenet
subjects	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION THERAPY FOR CANCER
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T11%3A50%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BREIJ%20Esther%20Cornelia%20Wilhelmina&rft.date=2024-02-07&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMX2024000674A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true