EGFR INHIBITOR FOR THE TREATMENT OF HEAD AND NECK CANCER

The invention relates to the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck (preferably recurrent squamous cell carcinoma of the head and neck) with a compound which is (3-ethynyl-phenyl)-[7-methoxy-6-(3- morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine (NRC-2694...

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Hauptverfasser: MYNENI Praveen Chowdary, YADLA Sheshu Babu, GOGULA Venkata Ramana, NANNAPANENI Venkaiah Chowdary
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creator MYNENI Praveen Chowdary
YADLA Sheshu Babu
GOGULA Venkata Ramana
NANNAPANENI Venkaiah Chowdary
description The invention relates to the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck (preferably recurrent squamous cell carcinoma of the head and neck) with a compound which is (3-ethynyl-phenyl)-[7-methoxy-6-(3- morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine (NRC-2694) or a pharmaceutically acceptable salt thereof. The invention also relates to the treatment of head and neck cancer with a compound which is (3-ethynyl-phenyl)-[7-methoxy-6-(3-morpholin-4-yl- propoxy)-quinazolin-4-yl]-amine (NRC-2694) or a pharmaceutically acceptable salt thereof, wherein the treating the head and neck cancer comprises reducing the size of one or more tumours associated with the head and neck cancer. La invención se refiere al tratamiento del carcinoma de células escamosas recurrente y/o metastásico de cabeza y cuello (preferentemente carcinoma de células 5 escamosas recurrente de cabeza y cuello) con un compuesto que es (3-etinil-fenil)-[7- metoxi-6-(3-morfolin-4-il-propoxi)-quinazolin-4-il]-amina (NRC-2694) o una sal farmacéuticamente aceptable del mismo. La invención también se refiere al tratamiento del cáncer de cabeza y cuello con un compuesto que es (3-etinil-fenil)-[7-metoxi-6-(3-m orfolin-4-il-propoxi)-quinazolin-4-il]-amina (NRC-2694) o una sal farmacéuticamente aceptable del 10 mismo, en donde el tratamiento del cáncer de cabeza y cuello comprende reducir el tamaño de uno o más tumores asociados al cáncer de cabeza y cuello.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title EGFR INHIBITOR FOR THE TREATMENT OF HEAD AND NECK CANCER
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