DEVICE AND METHOD FOR APPLYING PHOTOBIOMODULATION

The invention relates to a device for applying Photobiomodulation (PBM) on a biological object comprising a light source delivering light with an adequate temporal evolution of its optical power, said device also comprising a processing and/or a light control unit that determines the adequate temporal evolution of the optical power on the basis of the biological object optical coefficients and the light delivery geometry on/in the biological object, characterized by the fact that the PBM effects are induced by the generation of one or several specific fluence rates during one or several specific times, successively, in each parts of the volume of the biological object. said specific combined fluence rate(s) and said times being selected in the following groups of parameters : 3±2 mW/cm2 during 180±30 s or 11±9 mW/cm2 during 80±25 s or 16±10 mW/cm2 during 40±20 s or 25±10 mW/cm2 during 15±10 s or 10+9,7 mW/cm2 during 40±1 s. The invention also relates to different methods for applying (PBM) on a biological object comprising a light source delivering light with an adequate temporal evolution of its optical power as mentioned above. The invention also relates to device and methods mentioned above for applying PBM that are optionally used or applied with exogenous agents involved in, or modulating, the metabolism. The invention also relates to device and methods mentioned above for applying PBM that are optionally used or applied in combination with probes monitoring the metabolic activity taking place in the biological object. This monitoring enables to define the optimal PBM light applications conditions, in terms of: i) time relative to the metabolic activity, ii) fluence rate and iii) illumination duration. La invención se relaciona con un dispositivo para aplicar Fotobiomodulación (PBM) en un objeto biológico, que comprende una fuente de luz que suministra luz con una evolución temporal adecuada de su potencia óptica, el dispositivo también comprende una unidad de procesamiento y/o de control de la luz que determina la evolución temporal adecuada de la potencia óptica, basándose en los coeficientes ópticos del objeto biológico y en la geometría del suministro de la luz encima/en el objeto biológico, caracterizado por el hecho de que los efectos de la PBM son inducidos por la generación de una o varias tasas de la fluencia específicas, durante uno o varios tiempos específicos, de manera sucesiva, en cada una de las partes del volumen del objeto bi