SCHIFF BASE DERIVED FROM 4-AMINOBENZOIC ACID WITH A NET2 ELECTRON DONOR GROUP AND ITS USE AS AN IN VITRO FLUORESCENT STAINING AGENT

SCHIFF BASE DERIVED FROM 4-AMINOBENZOIC ACID WITH A NET2 ELECTRON DONOR GROUP AND ITS USE AS AN IN VITRO FLUORESCENT STAINING AGENT

The present invention aims to provide a Schiff base derived from 4-aminobenzoic acid and its ligand NEt2, synthesized by three different methods (conventional heating, mechanosynthesis, and ultrasound) and due to its low cytotoxicity, its use as a fluorescent marker agent in vitro to stain cell cyto...

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Bibliographische Detailangaben
Hauptverfasser: MUÑOZ FLORES Blanca Margarita, GÓMEZ TREVIÑO Jesús Alberto, JIMÉNEZ PÉREZ Víctor Manuel
Format: Patent
Sprache:eng ; spa
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ADHESIVES
CHEMISTRY
DYES
MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
ORGANIC CHEMISTRY
PAINTS
POLISHES
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Beschreibung
Zusammenfassung:The present invention aims to provide a Schiff base derived from 4-aminobenzoic acid and its ligand NEt2, synthesized by three different methods (conventional heating, mechanosynthesis, and ultrasound) and due to its low cytotoxicity, its use as a fluorescent marker agent in vitro to stain cell cytoplasm, making it a good candidate for obtaining fluorescent bioimages by confocal microscopy. La presente invención proporciona una base de Schiff derivada del ácido 4-aminobenzoico y su ligando NEt2, que es sintetizada por 3 métodos diferentes (calentamiento convencional, mecanosíntesis y ultrasonido) y debido a su baja citotoxicidad, se provee su uso como agente marcador fluorescente in vitro para teñir citoplasma de células, convirtiéndolo en buen candidato para la obtención de bioimágenes fluorescentes por microscopía confocal.