EPITOPIC VACCINE FOR AFRICAN SWINE FEVER VIRUS

The present disclosure generally relates to a T-cell epitope compounds and compositions effective against African Swine Fever Virus ("ASFV") and related diseases. Such T-cell epitope compounds and compositions include immunogenic T-cell epitope polypeptides (including concatemeric polypept...

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Hauptverfasser: GUTIERREZ Andres, MOISE Lenny, DE GROOT Anne, MARTIN William
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creator GUTIERREZ Andres
MOISE Lenny
DE GROOT Anne
MARTIN William
description The present disclosure generally relates to a T-cell epitope compounds and compositions effective against African Swine Fever Virus ("ASFV") and related diseases. Such T-cell epitope compounds and compositions include immunogenic T-cell epitope polypeptides (including concatemeric polypeptides and chimeric or fusion polypeptides), as well as nucleic acids, plasmids, vectors, and cells which express the polypeptides, pharmaceutical compositions, and vaccines, and the uses thereof. The present disclosure is particularly suited to produce vaccines for non-human animals, particularly for vaccinating swine against ASFV infection and related diseases. La presente divulgación se refiere de manera general a compuestos y composiciones de epítopos de células T eficaces contra virus de fiebre porcina africana (¿ASFV¿) y enfermedades relacionadas. Tales compuestos y composiciones de epítopos de células T incluyen polipéptidos de epítopos de células T inmunogénicos (que incluyen polipéptidos concateméricos y polipéptidos quiméricos o de fusión), así como ácidos nucleicos, plásmidos, vectores y células que expresan los polipéptidos, composiciones farmacéuticas y vacunas, y los usos de los mismos. La presente divulgación es adecuada en particular para producir vacunas para animales no humanos, en particular para vacunar cerdos contra infección de ASFV y enfermedades relacionadas.
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Such T-cell epitope compounds and compositions include immunogenic T-cell epitope polypeptides (including concatemeric polypeptides and chimeric or fusion polypeptides), as well as nucleic acids, plasmids, vectors, and cells which express the polypeptides, pharmaceutical compositions, and vaccines, and the uses thereof. The present disclosure is particularly suited to produce vaccines for non-human animals, particularly for vaccinating swine against ASFV infection and related diseases. La presente divulgación se refiere de manera general a compuestos y composiciones de epítopos de células T eficaces contra virus de fiebre porcina africana (¿ASFV¿) y enfermedades relacionadas. 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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title EPITOPIC VACCINE FOR AFRICAN SWINE FEVER VIRUS
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