AMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE
An amide derivative and an application thereof in medicine, specifically relating to the amide derivative represented by general formula (I) or a stereoisomer, solvate, a metabolic product, a deuterated product, a prodrug, a pharmaceutically acceptable salt or a co-crystal thereof, and a pharmaceuti...
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| creator | SUN Yi SU Guizhuan WEI Yonggang XIONG Lingfeng GAO Yue CHU Hongzhu WANG Meiwei |
| description | An amide derivative and an application thereof in medicine, specifically relating to the amide derivative represented by general formula (I) or a stereoisomer, solvate, a metabolic product, a deuterated product, a prodrug, a pharmaceutically acceptable salt or a co-crystal thereof, and a pharmaceutical composition containing same, and use of the compound or composition in the preparation of an NLRP3 inhibitor.
La presente invención se relaciona a un derivado de amida y uso del mismo en medicina, y específicamente a un derivado de amida mostrado como la fórmula general (I) o un estereoisómero, solvato, metabolito, deuterido, profármaco, sal o cocristal farmacéuticamente aceptable del mismo, una composición farmacéutica que contiene el mismo, y uso del compuesto o la composición descrita en la presente en la preparación de un inhibidor NLRP3 (ver Fórmula) (I). |
| format | Patent |
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La presente invención se relaciona a un derivado de amida y uso del mismo en medicina, y específicamente a un derivado de amida mostrado como la fórmula general (I) o un estereoisómero, solvato, metabolito, deuterido, profármaco, sal o cocristal farmacéuticamente aceptable del mismo, una composición farmacéutica que contiene el mismo, y uso del compuesto o la composición descrita en la presente en la preparación de un inhibidor NLRP3 (ver Fórmula) (I).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAhx9PV0cVVwcQ3yDHMM8QxzVXD0c1EICHINcAwC8v39FHxdQzz8XRRCPFyDXN38g8DyjgEBPp7OEHmwhL-bgidIqYuns6efKw8Da1piTnEqL5TmZlBycw1x9tBNLciPTy0uSExOzUstifeNMDIwMjIwMDU3NnI0JkoRAHg_MGc</recordid><startdate>20220609</startdate><enddate>20220609</enddate><creator>SUN Yi</creator><creator>SU Guizhuan</creator><creator>WEI Yonggang</creator><creator>XIONG Lingfeng</creator><creator>GAO Yue</creator><creator>CHU Hongzhu</creator><creator>WANG Meiwei</creator><scope>EVB</scope></search><sort><creationdate>20220609</creationdate><title>AMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE</title><author>SUN Yi ; SU Guizhuan ; WEI Yonggang ; XIONG Lingfeng ; GAO Yue ; CHU Hongzhu ; WANG Meiwei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2022005732A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SUN Yi</creatorcontrib><creatorcontrib>SU Guizhuan</creatorcontrib><creatorcontrib>WEI Yonggang</creatorcontrib><creatorcontrib>XIONG Lingfeng</creatorcontrib><creatorcontrib>GAO Yue</creatorcontrib><creatorcontrib>CHU Hongzhu</creatorcontrib><creatorcontrib>WANG Meiwei</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SUN Yi</au><au>SU Guizhuan</au><au>WEI Yonggang</au><au>XIONG Lingfeng</au><au>GAO Yue</au><au>CHU Hongzhu</au><au>WANG Meiwei</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE</title><date>2022-06-09</date><risdate>2022</risdate><abstract>An amide derivative and an application thereof in medicine, specifically relating to the amide derivative represented by general formula (I) or a stereoisomer, solvate, a metabolic product, a deuterated product, a prodrug, a pharmaceutically acceptable salt or a co-crystal thereof, and a pharmaceutical composition containing same, and use of the compound or composition in the preparation of an NLRP3 inhibitor.
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| language | eng ; spa |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE |
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