N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS
The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; spa |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SCHNUTE Mark Edward GERSTENBERGER Brian Stephen SCHMITT Daniel Copley UNWALLA Rayomand Jal ROBINSON JR. Ralph Pelton FLICK Andrew Christopher MOUSSEAU James John NUHANT Philippe Marcel WU Huixian KUNG Daniel Wei- Shung THORARENSEN Atli LOMBARDO Vincent Michael TRUJILLO John Isidro |
| description | The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of these compounds for treating or preventing diseases, conditions, or disorders ameliorated by inhibition of CCR6.
La presente invención se refiere a compuestos de dioxociclobutenilamino-3-hidroxi-picolinamida N-sustituida de las Fórmulas (IA y IB) (ver Fórmulas) Fórmula (IA) Fórmula (IB) o una sal o hidrato de aquellos aceptables desde el punto de vista farmacéutico, que inhiben el receptor de quimiocinas CC 6 (CCR6), a composiciones farmacéuticas que contienen estos compuestos, y al uso de estos compuestos para tratar o prevenir enfermedades, afecciones o trastornos que mejoran mediante inhibición de CCR6. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MX2021003318A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MX2021003318A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MX2021003318A3</originalsourceid><addsrcrecordid>eNqNirsKwjAUQLs4iPoPwT3QNiCueZVeSHOlNynNVIrESbRQ_x87-AFOh3M4-2LwnKKiACEGa7gBHFEn7VBt7pOTHXjkgrfJ9DgmfgONDvyWjSUWyTbRMUlM6_7CwLegIGBPx2L3mJ9rPv14KM6NDbrleXlPeV3me37lz9SNdVlXZSlEdZXir-kLbNwx7g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS</title><source>esp@cenet</source><creator>SCHNUTE Mark Edward ; GERSTENBERGER Brian Stephen ; SCHMITT Daniel Copley ; UNWALLA Rayomand Jal ; ROBINSON JR. Ralph Pelton ; FLICK Andrew Christopher ; MOUSSEAU James John ; NUHANT Philippe Marcel ; WU Huixian ; KUNG Daniel Wei- Shung ; THORARENSEN Atli ; LOMBARDO Vincent Michael ; TRUJILLO John Isidro</creator><creatorcontrib>SCHNUTE Mark Edward ; GERSTENBERGER Brian Stephen ; SCHMITT Daniel Copley ; UNWALLA Rayomand Jal ; ROBINSON JR. Ralph Pelton ; FLICK Andrew Christopher ; MOUSSEAU James John ; NUHANT Philippe Marcel ; WU Huixian ; KUNG Daniel Wei- Shung ; THORARENSEN Atli ; LOMBARDO Vincent Michael ; TRUJILLO John Isidro</creatorcontrib><description>The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of these compounds for treating or preventing diseases, conditions, or disorders ameliorated by inhibition of CCR6.
La presente invención se refiere a compuestos de dioxociclobutenilamino-3-hidroxi-picolinamida N-sustituida de las Fórmulas (IA y IB) (ver Fórmulas) Fórmula (IA) Fórmula (IB) o una sal o hidrato de aquellos aceptables desde el punto de vista farmacéutico, que inhiben el receptor de quimiocinas CC 6 (CCR6), a composiciones farmacéuticas que contienen estos compuestos, y al uso de estos compuestos para tratar o prevenir enfermedades, afecciones o trastornos que mejoran mediante inhibición de CCR6.</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210514&DB=EPODOC&CC=MX&NR=2021003318A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210514&DB=EPODOC&CC=MX&NR=2021003318A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SCHNUTE Mark Edward</creatorcontrib><creatorcontrib>GERSTENBERGER Brian Stephen</creatorcontrib><creatorcontrib>SCHMITT Daniel Copley</creatorcontrib><creatorcontrib>UNWALLA Rayomand Jal</creatorcontrib><creatorcontrib>ROBINSON JR. Ralph Pelton</creatorcontrib><creatorcontrib>FLICK Andrew Christopher</creatorcontrib><creatorcontrib>MOUSSEAU James John</creatorcontrib><creatorcontrib>NUHANT Philippe Marcel</creatorcontrib><creatorcontrib>WU Huixian</creatorcontrib><creatorcontrib>KUNG Daniel Wei- Shung</creatorcontrib><creatorcontrib>THORARENSEN Atli</creatorcontrib><creatorcontrib>LOMBARDO Vincent Michael</creatorcontrib><creatorcontrib>TRUJILLO John Isidro</creatorcontrib><title>N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS</title><description>The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of these compounds for treating or preventing diseases, conditions, or disorders ameliorated by inhibition of CCR6.
La presente invención se refiere a compuestos de dioxociclobutenilamino-3-hidroxi-picolinamida N-sustituida de las Fórmulas (IA y IB) (ver Fórmulas) Fórmula (IA) Fórmula (IB) o una sal o hidrato de aquellos aceptables desde el punto de vista farmacéutico, que inhiben el receptor de quimiocinas CC 6 (CCR6), a composiciones farmacéuticas que contienen estos compuestos, y al uso de estos compuestos para tratar o prevenir enfermedades, afecciones o trastornos que mejoran mediante inhibición de CCR6.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNirsKwjAUQLs4iPoPwT3QNiCueZVeSHOlNynNVIrESbRQ_x87-AFOh3M4-2LwnKKiACEGa7gBHFEn7VBt7pOTHXjkgrfJ9DgmfgONDvyWjSUWyTbRMUlM6_7CwLegIGBPx2L3mJ9rPv14KM6NDbrleXlPeV3me37lz9SNdVlXZSlEdZXir-kLbNwx7g</recordid><startdate>20210514</startdate><enddate>20210514</enddate><creator>SCHNUTE Mark Edward</creator><creator>GERSTENBERGER Brian Stephen</creator><creator>SCHMITT Daniel Copley</creator><creator>UNWALLA Rayomand Jal</creator><creator>ROBINSON JR. Ralph Pelton</creator><creator>FLICK Andrew Christopher</creator><creator>MOUSSEAU James John</creator><creator>NUHANT Philippe Marcel</creator><creator>WU Huixian</creator><creator>KUNG Daniel Wei- Shung</creator><creator>THORARENSEN Atli</creator><creator>LOMBARDO Vincent Michael</creator><creator>TRUJILLO John Isidro</creator><scope>EVB</scope></search><sort><creationdate>20210514</creationdate><title>N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS</title><author>SCHNUTE Mark Edward ; GERSTENBERGER Brian Stephen ; SCHMITT Daniel Copley ; UNWALLA Rayomand Jal ; ROBINSON JR. Ralph Pelton ; FLICK Andrew Christopher ; MOUSSEAU James John ; NUHANT Philippe Marcel ; WU Huixian ; KUNG Daniel Wei- Shung ; THORARENSEN Atli ; LOMBARDO Vincent Michael ; TRUJILLO John Isidro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2021003318A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SCHNUTE Mark Edward</creatorcontrib><creatorcontrib>GERSTENBERGER Brian Stephen</creatorcontrib><creatorcontrib>SCHMITT Daniel Copley</creatorcontrib><creatorcontrib>UNWALLA Rayomand Jal</creatorcontrib><creatorcontrib>ROBINSON JR. Ralph Pelton</creatorcontrib><creatorcontrib>FLICK Andrew Christopher</creatorcontrib><creatorcontrib>MOUSSEAU James John</creatorcontrib><creatorcontrib>NUHANT Philippe Marcel</creatorcontrib><creatorcontrib>WU Huixian</creatorcontrib><creatorcontrib>KUNG Daniel Wei- Shung</creatorcontrib><creatorcontrib>THORARENSEN Atli</creatorcontrib><creatorcontrib>LOMBARDO Vincent Michael</creatorcontrib><creatorcontrib>TRUJILLO John Isidro</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SCHNUTE Mark Edward</au><au>GERSTENBERGER Brian Stephen</au><au>SCHMITT Daniel Copley</au><au>UNWALLA Rayomand Jal</au><au>ROBINSON JR. Ralph Pelton</au><au>FLICK Andrew Christopher</au><au>MOUSSEAU James John</au><au>NUHANT Philippe Marcel</au><au>WU Huixian</au><au>KUNG Daniel Wei- Shung</au><au>THORARENSEN Atli</au><au>LOMBARDO Vincent Michael</au><au>TRUJILLO John Isidro</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS</title><date>2021-05-14</date><risdate>2021</risdate><abstract>The present invention relates to N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamide compounds of Formulae (IA and 1B) or a pharmaceutically acceptable salt or hydrate thereof, that inhibit CC chemokine receptor 6 (CCR6), pharmaceutical compositions containing these compounds, and the use of these compounds for treating or preventing diseases, conditions, or disorders ameliorated by inhibition of CCR6.
La presente invención se refiere a compuestos de dioxociclobutenilamino-3-hidroxi-picolinamida N-sustituida de las Fórmulas (IA y IB) (ver Fórmulas) Fórmula (IA) Fórmula (IB) o una sal o hidrato de aquellos aceptables desde el punto de vista farmacéutico, que inhiben el receptor de quimiocinas CC 6 (CCR6), a composiciones farmacéuticas que contienen estos compuestos, y al uso de estos compuestos para tratar o prevenir enfermedades, afecciones o trastornos que mejoran mediante inhibición de CCR6.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; spa |
| recordid | cdi_epo_espacenet_MX2021003318A |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T03%3A17%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SCHNUTE%20Mark%20Edward&rft.date=2021-05-14&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMX2021003318A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |