VACCINE COMPOSITIONS FOR USE AGAINST DIGITAL DERMATITIS IN A MAMMAL
The present invention provides new pharmaceutical and vaccine compositions comprising Treponema spp. bacterins,supplemented with antigens from Treponema spp.or other digital dermatitis causative pathological agents such as but not limited to D. nodosus or F. necrophorum,for effectively immunizing su...
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| creator | SERRA HARTMANN Xavier SITJÀ I ARNAU Marta QUEROL MURILLO Enrique FOIX BRETO Antoni PIÑOL RIBAS Jaume |
| description | The present invention provides new pharmaceutical and vaccine compositions comprising Treponema spp. bacterins,supplemented with antigens from Treponema spp.or other digital dermatitis causative pathological agents such as but not limited to D. nodosus or F. necrophorum,for effectively immunizing susceptible mammals, preferably ungulates, against DD, in particular against bovine digital dermatitis.The present invention also identifies Treponema pedis and Treponema phagedenis as two of the etiologic agents of digital dermatitis (DD) in mammals, in particular ungulate digital dermatitis. The invention therefore also provides isolated cultures of Treponema pedis and Treponema phagedenis for effectively immunizing susceptible mammals, preferably ungulates, against DD, in particular against bovine digital dermatitis. In addition, the present invention provides methods of diagnosing DD by detecting infection with a series of specific Treponema antigens.
La presente invención provee nuevas composiciones farmacéuticas y de vacuna que comprenden bacterinas de Treponema spp., suplementadas con antígenos provenientes de Treponema spp. u otros agentes patológicos causantes de dermatitis digital tales como, pero sin limitarse a, D. nodosus o F. necrophorum, para inmunizar de manera efectiva mamíferos susceptibles, de preferencia ungulados, contra DD, en particular contra dermatitis digital de bovino. La presente invención también identifica a Treponema pedis y Treponema phagedenis como dos de los agentes etiológicos de la dermatitis digital (DD) en mamíferos, en particular la dermatitis digital de los ungulados. Por lo tanto, la invención también provee cultivos aislados de Treponema pedis y Treponema phagedenis para inmunizar de manera efectiva mamíferos susceptibles, de preferencia ungulados, contra DD, en particular contra dermatitis digital de bovino. Además, la presente invención provee métodos para diagnosticar DD mediante la detección de infección con una serie de antígenos de Treponema específicos. |
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La presente invención provee nuevas composiciones farmacéuticas y de vacuna que comprenden bacterinas de Treponema spp., suplementadas con antígenos provenientes de Treponema spp. u otros agentes patológicos causantes de dermatitis digital tales como, pero sin limitarse a, D. nodosus o F. necrophorum, para inmunizar de manera efectiva mamíferos susceptibles, de preferencia ungulados, contra DD, en particular contra dermatitis digital de bovino. La presente invención también identifica a Treponema pedis y Treponema phagedenis como dos de los agentes etiológicos de la dermatitis digital (DD) en mamíferos, en particular la dermatitis digital de los ungulados. Por lo tanto, la invención también provee cultivos aislados de Treponema pedis y Treponema phagedenis para inmunizar de manera efectiva mamíferos susceptibles, de preferencia ungulados, contra DD, en particular contra dermatitis digital de bovino. Además, la presente invención provee métodos para diagnosticar DD mediante la detección de infección con una serie de antígenos de Treponema específicos.</description><language>eng ; spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201210&DB=EPODOC&CC=MX&NR=2020005104A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201210&DB=EPODOC&CC=MX&NR=2020005104A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SERRA HARTMANN Xavier</creatorcontrib><creatorcontrib>SITJÀ I ARNAU Marta</creatorcontrib><creatorcontrib>QUEROL MURILLO Enrique</creatorcontrib><creatorcontrib>FOIX BRETO Antoni</creatorcontrib><creatorcontrib>PIÑOL RIBAS Jaume</creatorcontrib><title>VACCINE COMPOSITIONS FOR USE AGAINST DIGITAL DERMATITIS IN A MAMMAL</title><description>The present invention provides new pharmaceutical and vaccine compositions comprising Treponema spp. bacterins,supplemented with antigens from Treponema spp.or other digital dermatitis causative pathological agents such as but not limited to D. nodosus or F. necrophorum,for effectively immunizing susceptible mammals, preferably ungulates, against DD, in particular against bovine digital dermatitis.The present invention also identifies Treponema pedis and Treponema phagedenis as two of the etiologic agents of digital dermatitis (DD) in mammals, in particular ungulate digital dermatitis. The invention therefore also provides isolated cultures of Treponema pedis and Treponema phagedenis for effectively immunizing susceptible mammals, preferably ungulates, against DD, in particular against bovine digital dermatitis. In addition, the present invention provides methods of diagnosing DD by detecting infection with a series of specific Treponema antigens.
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La presente invención provee nuevas composiciones farmacéuticas y de vacuna que comprenden bacterinas de Treponema spp., suplementadas con antígenos provenientes de Treponema spp. u otros agentes patológicos causantes de dermatitis digital tales como, pero sin limitarse a, D. nodosus o F. necrophorum, para inmunizar de manera efectiva mamíferos susceptibles, de preferencia ungulados, contra DD, en particular contra dermatitis digital de bovino. La presente invención también identifica a Treponema pedis y Treponema phagedenis como dos de los agentes etiológicos de la dermatitis digital (DD) en mamíferos, en particular la dermatitis digital de los ungulados. Por lo tanto, la invención también provee cultivos aislados de Treponema pedis y Treponema phagedenis para inmunizar de manera efectiva mamíferos susceptibles, de preferencia ungulados, contra DD, en particular contra dermatitis digital de bovino. Además, la presente invención provee métodos para diagnosticar DD mediante la detección de infección con una serie de antígenos de Treponema específicos.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | VACCINE COMPOSITIONS FOR USE AGAINST DIGITAL DERMATITIS IN A MAMMAL |
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