C5-ANILINOQUINAZOLINE COMPOUNDS AND THEIR USE IN TREATING CANCER

The invention concerns compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KIT mediated...

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Bibliographische Detailangaben
Hauptverfasser:	SMITH James Michael, KETTLE Jason Grant, PEARSON Stuart Eric, GRECU Tudor, PACKER Martin John
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention concerns compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KIT mediated diseases. La invención se refiere a compuestos de fórmula (I): (VER FORMULA I) o sales farmacéuticamente aceptables de los mismos, en donde R1, R2, R3 y R4 tienen cualquiera de los significados definidos anteriormente en el presente documento en la descripción; a procesos para su preparación; a composiciones farmacéuticas que los contienen y a su uso en el tratamiento de enfermedades mediadas por KIT.