PYRIMIDINE TRICYCLIC ENONE DERIVATIVES FOR INHIBITION OF RORy AND OTHER USES

Disclosed herein are compounds of the formulas: as well as analogs thereof, wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used to inhibit RORy and/or reduce the expression of IL-...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Bradley William CAPRATHE, Chitase LEE, Martha R. HOTEMA, Xin JIANG, Brian KORNBERG, Gary BOLTON, Christopher, F. BENDER, Zachary, S. SHELDON, Melean VISNICK
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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