TREATMENT OF SMALL CELL LUNG CANCER WITH A PARP INHIBITOR
Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11 ) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject,...
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| creator | Yuqiao SHEN Yuanbin RU Leonard E. POST Evelyn WANG Karen YU Ying FENG |
| description | Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11 ) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject, and administering effective amount of a PARP inhibitor, such as talazoparib or the tosylate salt of talazoparib, to the subject. :.
Se describen métodos para el tratamiento de un sujeto con cáncer de pulmón de células pequeñas que expresa Schlafen-11 (SLFN 11) con un inhibidor de poli(ADP-ribosa) polimerasas (PARP) o una sal farmacéuticamente aceptable del mismo. Específicamente, el método comprende la detección de SLFN 11 en una muestra de células tumorales del sujeto, y la administración al sujeto de una cantidad eficaz de un inhibidor de PARP, tal como talazoparib o la sal de tosilato de talazoparib. |
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Se describen métodos para el tratamiento de un sujeto con cáncer de pulmón de células pequeñas que expresa Schlafen-11 (SLFN 11) con un inhibidor de poli(ADP-ribosa) polimerasas (PARP) o una sal farmacéuticamente aceptable del mismo. Específicamente, el método comprende la detección de SLFN 11 en una muestra de células tumorales del sujeto, y la administración al sujeto de una cantidad eficaz de un inhibidor de PARP, tal como talazoparib o la sal de tosilato de talazoparib.</description><language>eng ; spa</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181129&DB=EPODOC&CC=MX&NR=2018005071A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181129&DB=EPODOC&CC=MX&NR=2018005071A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Yuqiao SHEN</creatorcontrib><creatorcontrib>Yuanbin RU</creatorcontrib><creatorcontrib>Leonard E. POST</creatorcontrib><creatorcontrib>Evelyn WANG</creatorcontrib><creatorcontrib>Karen YU</creatorcontrib><creatorcontrib>Ying FENG</creatorcontrib><title>TREATMENT OF SMALL CELL LUNG CANCER WITH A PARP INHIBITOR</title><description>Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11 ) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject, and administering effective amount of a PARP inhibitor, such as talazoparib or the tosylate salt of talazoparib, to the subject. :.
Se describen métodos para el tratamiento de un sujeto con cáncer de pulmón de células pequeñas que expresa Schlafen-11 (SLFN 11) con un inhibidor de poli(ADP-ribosa) polimerasas (PARP) o una sal farmacéuticamente aceptable del mismo. Específicamente, el método comprende la detección de SLFN 11 en una muestra de células tumorales del sujeto, y la administración al sujeto de una cantidad eficaz de un inhibidor de PARP, tal como talazoparib o la sal de tosilato de talazoparib.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAMCXJ1DPF19QtR8HdTCPZ19PFRcHYFEj6hfu4Kzo5-zq5BCuGeIR4KjgoBjkEBCp5-Hp5OniH-QTwMrGmJOcWpvFCam0HJzTXE2UM3tSA_PrW4IDE5NS-1JN43wsjA0MLAwNTA3NDRmChFALIiKNY</recordid><startdate>20181129</startdate><enddate>20181129</enddate><creator>Yuqiao SHEN</creator><creator>Yuanbin RU</creator><creator>Leonard E. POST</creator><creator>Evelyn WANG</creator><creator>Karen YU</creator><creator>Ying FENG</creator><scope>EVB</scope></search><sort><creationdate>20181129</creationdate><title>TREATMENT OF SMALL CELL LUNG CANCER WITH A PARP INHIBITOR</title><author>Yuqiao SHEN ; Yuanbin RU ; Leonard E. POST ; Evelyn WANG ; Karen YU ; Ying FENG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2018005071A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2018</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Yuqiao SHEN</creatorcontrib><creatorcontrib>Yuanbin RU</creatorcontrib><creatorcontrib>Leonard E. POST</creatorcontrib><creatorcontrib>Evelyn WANG</creatorcontrib><creatorcontrib>Karen YU</creatorcontrib><creatorcontrib>Ying FENG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Yuqiao SHEN</au><au>Yuanbin RU</au><au>Leonard E. POST</au><au>Evelyn WANG</au><au>Karen YU</au><au>Ying FENG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TREATMENT OF SMALL CELL LUNG CANCER WITH A PARP INHIBITOR</title><date>2018-11-29</date><risdate>2018</risdate><abstract>Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11 ) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject, and administering effective amount of a PARP inhibitor, such as talazoparib or the tosylate salt of talazoparib, to the subject. :.
Se describen métodos para el tratamiento de un sujeto con cáncer de pulmón de células pequeñas que expresa Schlafen-11 (SLFN 11) con un inhibidor de poli(ADP-ribosa) polimerasas (PARP) o una sal farmacéuticamente aceptable del mismo. Específicamente, el método comprende la detección de SLFN 11 en una muestra de células tumorales del sujeto, y la administración al sujeto de una cantidad eficaz de un inhibidor de PARP, tal como talazoparib o la sal de tosilato de talazoparib.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | TREATMENT OF SMALL CELL LUNG CANCER WITH A PARP INHIBITOR |
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