5'-SUBSTITUTED NUCLEOSIDE ANALOGS
The present invention relates to novel 5-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer, in particular glioblastomas, melanoma, sarcomas, gastric cancer, pancrea...
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creator | Karl Robert DAHNKE James Andrew JAMISON Brian Morgan WATSON Zahid Quyoom BONDAY Antonio RODRIGUEZ HERGUETA Guillermo S. CORTEZ Michael John GROGAN Timothy Andrew WOODS |
description | The present invention relates to novel 5-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer, in particular glioblastomas, melanoma, sarcomas, gastric cancer, pancreatic cancer, cholangiocarcinoma, bladder cancer, breast cancer, non-small cell lung cancer, leukemias including acute myeloid leukemia, and lymphomas.
La presente invención se refiere a compuestos de nucleósidos. 5'-sustituidos novedosos, composiciones farmacéuticas que comprenden los compuestos y métodos de utilización de los compuestos para tratar el cáncer, más particularmente para el tratamiento del cáncer, en particular los glioblastomas, melanoma, sarcomas, cáncer gástrico, cáncer de páncreas, colangiocarcinoma, cáncer de vejiga, cáncer de mama, cáncer de pulmón de células no pequeñas, leucemias, incluyendo leucemia mieloide aguda y los linfomas. |
format | Patent |
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La presente invención se refiere a compuestos de nucleósidos. 5'-sustituidos novedosos, composiciones farmacéuticas que comprenden los compuestos y métodos de utilización de los compuestos para tratar el cáncer, más particularmente para el tratamiento del cáncer, en particular los glioblastomas, melanoma, sarcomas, cáncer gástrico, cáncer de páncreas, colangiocarcinoma, cáncer de vejiga, cáncer de mama, cáncer de pulmón de células no pequeñas, leucemias, incluyendo leucemia mieloide aguda y los linfomas.</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180316&DB=EPODOC&CC=MX&NR=2017014001A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180316&DB=EPODOC&CC=MX&NR=2017014001A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Karl Robert DAHNKE</creatorcontrib><creatorcontrib>James Andrew JAMISON</creatorcontrib><creatorcontrib>Brian Morgan WATSON</creatorcontrib><creatorcontrib>Zahid Quyoom BONDAY</creatorcontrib><creatorcontrib>Antonio RODRIGUEZ HERGUETA</creatorcontrib><creatorcontrib>Guillermo S. CORTEZ</creatorcontrib><creatorcontrib>Michael John GROGAN</creatorcontrib><creatorcontrib>Timothy Andrew WOODS</creatorcontrib><title>5'-SUBSTITUTED NUCLEOSIDE ANALOGS</title><description>The present invention relates to novel 5-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer, in particular glioblastomas, melanoma, sarcomas, gastric cancer, pancreatic cancer, cholangiocarcinoma, bladder cancer, breast cancer, non-small cell lung cancer, leukemias including acute myeloid leukemia, and lymphomas.
La presente invención se refiere a compuestos de nucleósidos. 5'-sustituidos novedosos, composiciones farmacéuticas que comprenden los compuestos y métodos de utilización de los compuestos para tratar el cáncer, más particularmente para el tratamiento del cáncer, en particular los glioblastomas, melanoma, sarcomas, cáncer gástrico, cáncer de páncreas, colangiocarcinoma, cáncer de vejiga, cáncer de mama, cáncer de pulmón de células no pequeñas, leucemias, incluyendo leucemia mieloide aguda y los linfomas.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFA0VdcNDnUKDvEMCQ1xdVHwC3X2cfUP9nRxVXD0c_Txdw_mYWBNS8wpTuWF0twMSm6uIc4euqkF-fGpxQWJyal5qSXxvhFGBobmBoYmBgaGjsZEKQIAVJIiiw</recordid><startdate>20180316</startdate><enddate>20180316</enddate><creator>Karl Robert DAHNKE</creator><creator>James Andrew JAMISON</creator><creator>Brian Morgan WATSON</creator><creator>Zahid Quyoom BONDAY</creator><creator>Antonio RODRIGUEZ HERGUETA</creator><creator>Guillermo S. CORTEZ</creator><creator>Michael John GROGAN</creator><creator>Timothy Andrew WOODS</creator><scope>EVB</scope></search><sort><creationdate>20180316</creationdate><title>5'-SUBSTITUTED NUCLEOSIDE ANALOGS</title><author>Karl Robert DAHNKE ; James Andrew JAMISON ; Brian Morgan WATSON ; Zahid Quyoom BONDAY ; Antonio RODRIGUEZ HERGUETA ; Guillermo S. CORTEZ ; Michael John GROGAN ; Timothy Andrew WOODS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2017014001A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Karl Robert DAHNKE</creatorcontrib><creatorcontrib>James Andrew JAMISON</creatorcontrib><creatorcontrib>Brian Morgan WATSON</creatorcontrib><creatorcontrib>Zahid Quyoom BONDAY</creatorcontrib><creatorcontrib>Antonio RODRIGUEZ HERGUETA</creatorcontrib><creatorcontrib>Guillermo S. CORTEZ</creatorcontrib><creatorcontrib>Michael John GROGAN</creatorcontrib><creatorcontrib>Timothy Andrew WOODS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Karl Robert DAHNKE</au><au>James Andrew JAMISON</au><au>Brian Morgan WATSON</au><au>Zahid Quyoom BONDAY</au><au>Antonio RODRIGUEZ HERGUETA</au><au>Guillermo S. CORTEZ</au><au>Michael John GROGAN</au><au>Timothy Andrew WOODS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>5'-SUBSTITUTED NUCLEOSIDE ANALOGS</title><date>2018-03-16</date><risdate>2018</risdate><abstract>The present invention relates to novel 5-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer, in particular glioblastomas, melanoma, sarcomas, gastric cancer, pancreatic cancer, cholangiocarcinoma, bladder cancer, breast cancer, non-small cell lung cancer, leukemias including acute myeloid leukemia, and lymphomas.
La presente invención se refiere a compuestos de nucleósidos. 5'-sustituidos novedosos, composiciones farmacéuticas que comprenden los compuestos y métodos de utilización de los compuestos para tratar el cáncer, más particularmente para el tratamiento del cáncer, en particular los glioblastomas, melanoma, sarcomas, cáncer gástrico, cáncer de páncreas, colangiocarcinoma, cáncer de vejiga, cáncer de mama, cáncer de pulmón de células no pequeñas, leucemias, incluyendo leucemia mieloide aguda y los linfomas.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 5'-SUBSTITUTED NUCLEOSIDE ANALOGS |
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