SOCS1-DERIVED PEPTIDE FOR USE IN CHRONIC COMPLICATIONS RELATING TO DIABETES

The invention relates to a SOCS1-derived peptide for use in chronic complications relating to diabetes, especially ocular, renal, nervous and vascular complications, and to compositions containing said peptide and isolated polynucleotides encoding for said peptide. The invention also relates to the...

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Hauptverfasser: Cristina HERNÁNDEZ PASCUAL, Jesús EGIDO DE LOS RÍOS, Rafael SIMÓ CANONGE, Carmen GÓMEZ GUERRERO
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creator Cristina HERNÁNDEZ PASCUAL
Jesús EGIDO DE LOS RÍOS
Rafael SIMÓ CANONGE
Carmen GÓMEZ GUERRERO
description The invention relates to a SOCS1-derived peptide for use in chronic complications relating to diabetes, especially ocular, renal, nervous and vascular complications, and to compositions containing said peptide and isolated polynucleotides encoding for said peptide. The invention also relates to the topical use of said SOCS1-derived peptide in the treatment and/or prevention of neurodegenerative diseases of the retina, especially in the first stages of diabetic retinopathy and retina-related diseases wherein neurodegeneration plays an essential role. Péptido derivado de SOCS1 para su uso en complicaciones crónicas de la diabetes, especialmente complicaciones oculares, renales, nerviosas y vasculares, así como composiciones que lo contienen y polinucleótidos aislados que lo codifican. La presente invención también se refiere al péptido derivado de SOCS1 para su uso tópico en el tratamiento y/o prevención de enfermedades neurodegenerativas de la retina, en particular en las primeras etapas de la retinopatía diabética y otras enfermedades de la retina en las que la neurodegeneración juega un papel esencial.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SOCS1-DERIVED PEPTIDE FOR USE IN CHRONIC COMPLICATIONS RELATING TO DIABETES
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