COMPOSITION COMPRISING AN ENCAPSULATED ANTAGOMIR

The invention relates to a composition comprising an effective amount of at least one inhibitor of a miRNA involved in the angiogenesis, or a precursor thereof, wherein said inhibitor is microencapsulated into polymeric biodegradable and biocompatible microspheres. The invention also relates to the...

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Hauptverfasser: AMADEO PEREZ, NEUS BELLERA GOTARDA, ANTONIO DAVID GARCIA-DORADO GARCIA, ANTONIO RODRIGUEZ SINOVAS, IGNASI BARBA VERT, MIGUEL-ANGEL ASIN, EULALIA FERRET
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creator AMADEO PEREZ
NEUS BELLERA GOTARDA
ANTONIO DAVID GARCIA-DORADO GARCIA
ANTONIO RODRIGUEZ SINOVAS
IGNASI BARBA VERT
MIGUEL-ANGEL ASIN
EULALIA FERRET
description The invention relates to a composition comprising an effective amount of at least one inhibitor of a miRNA involved in the angiogenesis, or a precursor thereof, wherein said inhibitor is microencapsulated into polymeric biodegradable and biocompatible microspheres. The invention also relates to the use of the said composition for preventing or treating cardiac disorders, including cardiac disorders caused by ischemy. La presente invención se relaciona con una composición que comprende una cantidad efectiva de por lo menos un inhibidor de un ARNmi involucrado en la angiogénesis, o un precursor del mismo, en donde el inhibidor se microencapsula en microesferas poliméricas biodegradables y biocompatibles. La invención también se relaciona con el uso de tal composición para prevenir o tratar trastornos cardiacos, que incluyen trastornos cardiacos causados por isquemia.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title COMPOSITION COMPRISING AN ENCAPSULATED ANTAGOMIR
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