NOVEL COMPOUNDS

The present invention discloses novel compounds inhibiting LRRK2 kinase activity, the preparation processes thereof, the compositions containing them, as well as the use in treating diseases characterized by LRRK2 kinase activity, particularly Parkinson's disease and Alzheimer's disease. L...

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Hauptverfasser: JANDU, KARAMJIT SINGH, NICHOLS, PAULA LOUISE, EATHERTON, ANDREW JOHN, ANDREOTTI, DANIELE, PHILPS, OLIVER JAMES, BAMBOROUGH, PAUL
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creator JANDU, KARAMJIT SINGH
NICHOLS, PAULA LOUISE
EATHERTON, ANDREW JOHN
ANDREOTTI, DANIELE
PHILPS, OLIVER JAMES
BAMBOROUGH, PAUL
description The present invention discloses novel compounds inhibiting LRRK2 kinase activity, the preparation processes thereof, the compositions containing them, as well as the use in treating diseases characterized by LRRK2 kinase activity, particularly Parkinson's disease and Alzheimer's disease. La presente invención describe compuestos novedosos que inhiben la actividad de LRRK2 cinasa, los procedimientos de preparación de los mismos, las composiciones que los contienen, así como el uso en el tratamiento de enfermedades caracterizadas por actividad de LRRK2 cinasa, particularmente enfermedad de Parkinson y enfermedad de Alzheimer.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL COMPOUNDS
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