AMINO ARYLSULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS FIELD OF INVENTION

The present invention relates to novel amino arylsulfonamide compounds of the formula (I), their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them: The present invention also relates to a process for the preparation of above said novel compounds, their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The compounds of the invention are useful in the treatment of various disorders that are related to 5-HT6 receptor functions. Specifically, the compounds of this invention are also useful in the treatment of various CNS disorders, hematological disorders, eating disorders, obesity, anxiety, depression, diseases associated with pain, respiratory diseases, gastrointestinal, cardiovascular diseases and cancer. La presente invenci?n se relaciona con compuestos novedosos de aminoarilsulfonamida de la f?rmula (I), sus derivados, sus estereois?meros, sus sales farmac?uticamente aceptables y las composiciones farmac?uticamente aceptables que los contienen. La presente invenci?n tambi?n se relaciona con un proceso para la preparaci?n de los compuestos novedosos anteriores, sus derivados, sus estereois?meros, sus sales farmac?uticamente aceptables y las composiciones farmac?uticamente aceptables que los contienen. Los compuestos de la invenci?n son ?tiles en el tratamiento de varios trastornos que est?n relacionados con las funciones del receptor de 5-HT6. De manera espec?fica, los compuestos de esta invenci?n tambi?n son ?tiles en el tratamiento de varios trastornos del CNS, trastornos hematol?gicos, trastornos de la alimentaci?n, obesidad, ansiedad, depresi?n, enfermedades asociadas con el dolor, enfermedades respiratorias, enfermedades gastrointestinales, cardiovasculares y c?ncer.