HETEROARYL SIK INHIBITORS
The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bo...
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| creator | KLICIC, Jasna NAPIER, Spencer DAHMANN, Georg MCCARTHY, Clive WALKER, Edward SWANTEK FITZGERALD, Jennifer L HOFFMANN, Matthias SCOTT, John LAMB, David James PARRISH, Karen |
| description | The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis. |
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PARRISH, Karen</creatorcontrib><description>The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200120&DB=EPODOC&CC=ME&NR=03472B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200120&DB=EPODOC&CC=ME&NR=03472B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KLICIC, Jasna</creatorcontrib><creatorcontrib>NAPIER, Spencer</creatorcontrib><creatorcontrib>DAHMANN, Georg</creatorcontrib><creatorcontrib>MCCARTHY, Clive</creatorcontrib><creatorcontrib>WALKER, Edward</creatorcontrib><creatorcontrib>SWANTEK FITZGERALD, Jennifer L</creatorcontrib><creatorcontrib>HOFFMANN, Matthias</creatorcontrib><creatorcontrib>SCOTT, John</creatorcontrib><creatorcontrib>LAMB, David James</creatorcontrib><creatorcontrib>PARRISH, Karen</creatorcontrib><title>HETEROARYL SIK INHIBITORS</title><description>The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJD0cA1xDfJ3DIr0UQj29Fbw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDLJuriHOHrqpBfnxqcUFicmpeakl8b6uBsYm5kZOxoTkATJhHn0</recordid><startdate>20200120</startdate><enddate>20200120</enddate><creator>KLICIC, Jasna</creator><creator>NAPIER, Spencer</creator><creator>DAHMANN, Georg</creator><creator>MCCARTHY, Clive</creator><creator>WALKER, Edward</creator><creator>SWANTEK FITZGERALD, Jennifer L</creator><creator>HOFFMANN, Matthias</creator><creator>SCOTT, John</creator><creator>LAMB, David James</creator><creator>PARRISH, Karen</creator><scope>EVB</scope></search><sort><creationdate>20200120</creationdate><title>HETEROARYL SIK INHIBITORS</title><author>KLICIC, Jasna ; NAPIER, Spencer ; DAHMANN, Georg ; MCCARTHY, Clive ; WALKER, Edward ; SWANTEK FITZGERALD, Jennifer L ; HOFFMANN, Matthias ; SCOTT, John ; LAMB, David James ; PARRISH, Karen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ME03472B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KLICIC, Jasna</creatorcontrib><creatorcontrib>NAPIER, Spencer</creatorcontrib><creatorcontrib>DAHMANN, Georg</creatorcontrib><creatorcontrib>MCCARTHY, Clive</creatorcontrib><creatorcontrib>WALKER, Edward</creatorcontrib><creatorcontrib>SWANTEK FITZGERALD, Jennifer L</creatorcontrib><creatorcontrib>HOFFMANN, Matthias</creatorcontrib><creatorcontrib>SCOTT, John</creatorcontrib><creatorcontrib>LAMB, David James</creatorcontrib><creatorcontrib>PARRISH, Karen</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KLICIC, Jasna</au><au>NAPIER, Spencer</au><au>DAHMANN, Georg</au><au>MCCARTHY, Clive</au><au>WALKER, Edward</au><au>SWANTEK FITZGERALD, Jennifer L</au><au>HOFFMANN, Matthias</au><au>SCOTT, John</au><au>LAMB, David James</au><au>PARRISH, Karen</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HETEROARYL SIK INHIBITORS</title><date>2020-01-20</date><risdate>2020</risdate><abstract>The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HETEROARYL SIK INHIBITORS |
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