Glp-1 receptor agonists and uses thereof

Glp-1 receptor agonists and uses thereof

Prezenta invenţie se referă la acizi 6-carboxilici ai benzimidazolilor şi la 4-aza-, 5-aza-, 7-aza- şi 4,7-diaza-benzimidazoli оn calitate de agonişti GLP-1R, la procedee de obţinere a compuşilor menţionaţi şi la metode care includ administrarea compuşilor menţionaţi la un mamifer, care are nevoie d...

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Hauptverfasser: RUGGERI Roger B, FLANAGAN Mark E, DOWLING Matthew S, INGLE Gajendra, ASPNES Gary Erik, HUARD Kim, CURTO John M, LIMBERAKIS Chris, JIAO Wenhua, BAGLEY Scott W, FUTATSUGI Kentaro, MATHIOWETZ Alan M, PIOTROWSKI David W, EDMONDS David James, GRIFFITH David A
Format: Patent
Sprache:eng ; rum
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Prezenta invenţie se referă la acizi 6-carboxilici ai benzimidazolilor şi la 4-aza-, 5-aza-, 7-aza- şi 4,7-diaza-benzimidazoli оn calitate de agonişti GLP-1R, la procedee de obţinere a compuşilor menţionaţi şi la metode care includ administrarea compuşilor menţionaţi la un mamifer, care are nevoie de aceasta. Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.