Indole and indazole compounds that activate AMPK
The invention relates to indole and indazole compounds of Formula (I):that activate 5´ adenosine monophosphate-activated kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions or disorders ameli...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rum ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | BHATTACHARYA Samit Kumar DOWLING Matthew Scott KUNG Daniel Wei-Shung CAMERON Kimberly O'Keefe FERNANDO Dilinie Prasadhini SMITH Aaron Christopher EBNER David Christopher FILIPSKI Kevin James TU Meihua Mike LEE Esther Cheng Yin |
| description | The invention relates to indole and indazole compounds of Formula (I):that activate 5´ adenosine monophosphate-activated kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions or disorders ameliorated by activation of AMPK.
Invenţia se referă la compuşi ai indolului şi indazolului cu formula (I):care activează protein-kinaza stimulată de 5' adenozin monofosfat (AMPK). Invenţia se mai referă la compoziţii farmaceutice care conţin aceşti compuşi şi la metode de tratare sau prevenire a bolilor, stărilor sau tulburărilor, intensitatea simptomelor cărora scade prin activarea AMPK.
Изобретение относится к соединениям индола и индазола формулы (I):активирующим 5'-аденозин-монофосфат-активируемую протеинкиназу (AMPK). Изобретение также относится к фармацевтическим композициям, содержащим эти соединения, и к методам лечения или предупреждения заболеваний, состояний или расстройств, интенсивность симптомов которых уменьшается посредством активации AMPK. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MD20140109A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MD20140109A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MD20140109A23</originalsourceid><addsrcrecordid>eNrjZDDwzEvJz0lVSMxLUcjMS0msAnGS83ML8kvzUooVSjISSxQSk0syyxJLUhUcfQO8eRhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJvK-LkYGhiYGhgaWjkTExagAo1yqk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Indole and indazole compounds that activate AMPK</title><source>esp@cenet</source><creator>BHATTACHARYA Samit Kumar ; DOWLING Matthew Scott ; KUNG Daniel Wei-Shung ; CAMERON Kimberly O'Keefe ; FERNANDO Dilinie Prasadhini ; SMITH Aaron Christopher ; EBNER David Christopher ; FILIPSKI Kevin James ; TU Meihua Mike ; LEE Esther Cheng Yin</creator><creatorcontrib>BHATTACHARYA Samit Kumar ; DOWLING Matthew Scott ; KUNG Daniel Wei-Shung ; CAMERON Kimberly O'Keefe ; FERNANDO Dilinie Prasadhini ; SMITH Aaron Christopher ; EBNER David Christopher ; FILIPSKI Kevin James ; TU Meihua Mike ; LEE Esther Cheng Yin</creatorcontrib><description>The invention relates to indole and indazole compounds of Formula (I):that activate 5´ adenosine monophosphate-activated kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions or disorders ameliorated by activation of AMPK.
Invenţia se referă la compuşi ai indolului şi indazolului cu formula (I):care activează protein-kinaza stimulată de 5' adenozin monofosfat (AMPK). Invenţia se mai referă la compoziţii farmaceutice care conţin aceşti compuşi şi la metode de tratare sau prevenire a bolilor, stărilor sau tulburărilor, intensitatea simptomelor cărora scade prin activarea AMPK.
Изобретение относится к соединениям индола и индазола формулы (I):активирующим 5'-аденозин-монофосфат-активируемую протеинкиназу (AMPK). Изобретение также относится к фармацевтическим композициям, содержащим эти соединения, и к методам лечения или предупреждения заболеваний, состояний или расстройств, интенсивность симптомов которых уменьшается посредством активации AMPK.</description><language>eng ; rum ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150228&DB=EPODOC&CC=MD&NR=20140109A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150228&DB=EPODOC&CC=MD&NR=20140109A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BHATTACHARYA Samit Kumar</creatorcontrib><creatorcontrib>DOWLING Matthew Scott</creatorcontrib><creatorcontrib>KUNG Daniel Wei-Shung</creatorcontrib><creatorcontrib>CAMERON Kimberly O'Keefe</creatorcontrib><creatorcontrib>FERNANDO Dilinie Prasadhini</creatorcontrib><creatorcontrib>SMITH Aaron Christopher</creatorcontrib><creatorcontrib>EBNER David Christopher</creatorcontrib><creatorcontrib>FILIPSKI Kevin James</creatorcontrib><creatorcontrib>TU Meihua Mike</creatorcontrib><creatorcontrib>LEE Esther Cheng Yin</creatorcontrib><title>Indole and indazole compounds that activate AMPK</title><description>The invention relates to indole and indazole compounds of Formula (I):that activate 5´ adenosine monophosphate-activated kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions or disorders ameliorated by activation of AMPK.
Invenţia se referă la compuşi ai indolului şi indazolului cu formula (I):care activează protein-kinaza stimulată de 5' adenozin monofosfat (AMPK). Invenţia se mai referă la compoziţii farmaceutice care conţin aceşti compuşi şi la metode de tratare sau prevenire a bolilor, stărilor sau tulburărilor, intensitatea simptomelor cărora scade prin activarea AMPK.
Изобретение относится к соединениям индола и индазола формулы (I):активирующим 5'-аденозин-монофосфат-активируемую протеинкиназу (AMPK). Изобретение также относится к фармацевтическим композициям, содержащим эти соединения, и к методам лечения или предупреждения заболеваний, состояний или расстройств, интенсивность симптомов которых уменьшается посредством активации AMPK.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDwzEvJz0lVSMxLUcjMS0msAnGS83ML8kvzUooVSjISSxQSk0syyxJLUhUcfQO8eRhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJvK-LkYGhiYGhgaWjkTExagAo1yqk</recordid><startdate>20150228</startdate><enddate>20150228</enddate><creator>BHATTACHARYA Samit Kumar</creator><creator>DOWLING Matthew Scott</creator><creator>KUNG Daniel Wei-Shung</creator><creator>CAMERON Kimberly O'Keefe</creator><creator>FERNANDO Dilinie Prasadhini</creator><creator>SMITH Aaron Christopher</creator><creator>EBNER David Christopher</creator><creator>FILIPSKI Kevin James</creator><creator>TU Meihua Mike</creator><creator>LEE Esther Cheng Yin</creator><scope>EVB</scope></search><sort><creationdate>20150228</creationdate><title>Indole and indazole compounds that activate AMPK</title><author>BHATTACHARYA Samit Kumar ; DOWLING Matthew Scott ; KUNG Daniel Wei-Shung ; CAMERON Kimberly O'Keefe ; FERNANDO Dilinie Prasadhini ; SMITH Aaron Christopher ; EBNER David Christopher ; FILIPSKI Kevin James ; TU Meihua Mike ; LEE Esther Cheng Yin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MD20140109A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rum ; rus</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BHATTACHARYA Samit Kumar</creatorcontrib><creatorcontrib>DOWLING Matthew Scott</creatorcontrib><creatorcontrib>KUNG Daniel Wei-Shung</creatorcontrib><creatorcontrib>CAMERON Kimberly O'Keefe</creatorcontrib><creatorcontrib>FERNANDO Dilinie Prasadhini</creatorcontrib><creatorcontrib>SMITH Aaron Christopher</creatorcontrib><creatorcontrib>EBNER David Christopher</creatorcontrib><creatorcontrib>FILIPSKI Kevin James</creatorcontrib><creatorcontrib>TU Meihua Mike</creatorcontrib><creatorcontrib>LEE Esther Cheng Yin</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BHATTACHARYA Samit Kumar</au><au>DOWLING Matthew Scott</au><au>KUNG Daniel Wei-Shung</au><au>CAMERON Kimberly O'Keefe</au><au>FERNANDO Dilinie Prasadhini</au><au>SMITH Aaron Christopher</au><au>EBNER David Christopher</au><au>FILIPSKI Kevin James</au><au>TU Meihua Mike</au><au>LEE Esther Cheng Yin</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Indole and indazole compounds that activate AMPK</title><date>2015-02-28</date><risdate>2015</risdate><abstract>The invention relates to indole and indazole compounds of Formula (I):that activate 5´ adenosine monophosphate-activated kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions or disorders ameliorated by activation of AMPK.
Invenţia se referă la compuşi ai indolului şi indazolului cu formula (I):care activează protein-kinaza stimulată de 5' adenozin monofosfat (AMPK). Invenţia se mai referă la compoziţii farmaceutice care conţin aceşti compuşi şi la metode de tratare sau prevenire a bolilor, stărilor sau tulburărilor, intensitatea simptomelor cărora scade prin activarea AMPK.
Изобретение относится к соединениям индола и индазола формулы (I):активирующим 5'-аденозин-монофосфат-активируемую протеинкиназу (AMPK). Изобретение также относится к фармацевтическим композициям, содержащим эти соединения, и к методам лечения или предупреждения заболеваний, состояний или расстройств, интенсивность симптомов которых уменьшается посредством активации AMPK.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rum ; rus |
| recordid | cdi_epo_espacenet_MD20140109A2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Indole and indazole compounds that activate AMPK |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T23%3A27%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BHATTACHARYA%20Samit%20Kumar&rft.date=2015-02-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMD20140109A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |