Inhibiteurs de cdk8/19

La présente invention concerne de nouveaux composés correspondant à la formule (i) qui possèdent des propriétés d'inhibiteur de cdk8/19, ainsi que des compositions pharmaceutiques contenant lesdits composés, et leur utilisation en qualité de préparations pharmaceutiques pour traiter des affecti...

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Hauptverfasser: KASATKINA, Mariia Andreevna, CHESTNOVA, Anna Jur'evna, SMIRNOV, Evgenii Jur'evich, GAVRILOV, Aleksei Sergeevich, IAKOVLEV, Pavel Andreevich, ALAFINOV, Andrei Ivanovich, MOROZOV, Dmitry Valentinovich, MINDICH, Aleksei Leonidovich, SILONOV, Sergei Aleksandrovich, LENSHMIDT, Liliana Vyacheslavovna, EVDOKIMOV, Anton Aleksandrovich, MAKSIMENKO, Elena Aleksandrovna, MISHINA, Mariia Sergeevna
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creator KASATKINA, Mariia Andreevna
CHESTNOVA, Anna Jur'evna
SMIRNOV, Evgenii Jur'evich
GAVRILOV, Aleksei Sergeevich
IAKOVLEV, Pavel Andreevich
ALAFINOV, Andrei Ivanovich
MOROZOV, Dmitry Valentinovich
MINDICH, Aleksei Leonidovich
SILONOV, Sergei Aleksandrovich
LENSHMIDT, Liliana Vyacheslavovna
EVDOKIMOV, Anton Aleksandrovich
MAKSIMENKO, Elena Aleksandrovna
MISHINA, Mariia Sergeevna
description La présente invention concerne de nouveaux composés correspondant à la formule (i) qui possèdent des propriétés d'inhibiteur de cdk8/19, ainsi que des compositions pharmaceutiques contenant lesdits composés, et leur utilisation en qualité de préparations pharmaceutiques pour traiter des affections ou des troubles. The present invention relates to novel compounds of formula I:which have the properties of CDK8/19 inhibitors, to a pharmaceutical composition comprising said compounds, and to use thereof as a medicine for treating diseases and disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Inhibiteurs de cdk8/19
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