INHIBITEURS SÉLECTIFS DE L'ISOFORME TGFBETA1 ET UTILISATION ASSOCIÉE

Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.

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Hauptverfasser: CHAPRON, Christopher, WAWERSIK, Stefan, STEIN, Caitlin, BUCKLER, Alan, COOPER, Anthony, LIN, Susan, SCHURPF, Thomas, DAGBAY, Kevin B, CAPILI, Allan, JACKSON, Justin W, DATTA, Abhishek, SALOTTO, Matthew, AVERY, Andrew, MARTIN, Constance, CARVEN, Gregory J, LITTLEFIELD, Christopher
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creator CHAPRON, Christopher
WAWERSIK, Stefan
STEIN, Caitlin
BUCKLER, Alan
COOPER, Anthony
LIN, Susan
SCHURPF, Thomas
DAGBAY, Kevin B
CAPILI, Allan
JACKSON, Justin W
DATTA, Abhishek
SALOTTO, Matthew
AVERY, Andrew
MARTIN, Constance
CARVEN, Gregory J
LITTLEFIELD, Christopher
description Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGFβ1 with high potency. Related compositions, methods and therapeutic use are also disclosed.
format Patent
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INHIBITEURS SÉLECTIFS DE L'ISOFORME TGFBETA1 ET UTILISATION ASSOCIÉE
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