COMPOSÉS DE [1,2,4]TRIAZOLO [1,5-A]PYRIMIDINE EN TANT QU'INHIBITEURS DE PDE2

The present invention relates to novel [1,2,4]triazolo[1,5-a]pyrimidin-yl derivatives as inhibitors of phosphodiesterase 2 (PDE2). The invention is also directed to pharmaceutical compositions comprising the compounds, to processes for preparing such compounds and compositions, and to the use of suc...

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Hauptverfasser: BUIJNSTERS, Peter, Jacobus, Johannes, Antonius, TRESADERN, Gary, John, GIJSEN, Henricus, Jacobus, Maria, VAN DEN KEYBUS, Frans, Alfons, Maria, VELTER, Adriana, Ingrid, VAN ROOSBROECK, Yves, Emiel, Maria
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creator BUIJNSTERS, Peter, Jacobus, Johannes, Antonius
TRESADERN, Gary, John
GIJSEN, Henricus, Jacobus, Maria
VAN DEN KEYBUS, Frans, Alfons, Maria
VELTER, Adriana, Ingrid
VAN ROOSBROECK, Yves, Emiel, Maria
description The present invention relates to novel [1,2,4]triazolo[1,5-a]pyrimidin-yl derivatives as inhibitors of phosphodiesterase 2 (PDE2). The invention is also directed to pharmaceutical compositions comprising the compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which PDE2 is involved, such as neurological and psychiatric disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSÉS DE [1,2,4]TRIAZOLO [1,5-A]PYRIMIDINE EN TANT QU'INHIBITEURS DE PDE2
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