PROCEDE DE PREPARATION DES NOUVEAUX COMPOSES REPONDANT A LA FORMULE I
Novel 7-alkyl- DELTA 4-17 alpha -pregnene-3-ones of the formula I wherein R is selected from the group consisting of saturated and unsaturated alkyl of 2 to 8 carbon atoms, cycloalkyl alkyl of 4 to 8 carbon atoms and arylalkyl of 7 to 12 carbon atoms and X and Y form the group or X is OH and Y is an...
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Zusammenfassung: | Novel 7-alkyl- DELTA 4-17 alpha -pregnene-3-ones of the formula I wherein R is selected from the group consisting of saturated and unsaturated alkyl of 2 to 8 carbon atoms, cycloalkyl alkyl of 4 to 8 carbon atoms and arylalkyl of 7 to 12 carbon atoms and X and Y form the group or X is OH and Y is and M is selected from the group consisting of hydrogen, alkali metal and NH4 and the wavy line indicates the alpha - or beta -position or mixtures thereof having aldosterone antagonistic activity and increased hydrosodium diuresis with organic potassium conservation while devoid of secondary hormonal effects and their preparation. |
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