METHOD FOR PRODUCTION OF LENALIDOMIDE

Improvements for production of 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindole-2-yl)piperidine-2,6-dione (lenalidomide) are disclosed, that include bromination of methyl 2-methyl-3-nitro-benzoate with N-bromosuccinimide in methyl acetate solution and obtaining end-product by reduction of 3-(4-nitro-1-oxo-...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	EBEDEVS ANTONS, PONOMARJOVS JURIJS, KALVI Š IVARS, ERNOBROVIJS ALEKSANDRS, VARA EVA LARISA
Format:	Patent
Sprache:	eng ; lav
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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