A pan-KRAS inhibitor compound

The present invention relates to a pan-KRAS inhibitor compound represented by formula (I) or formula (II) and a pharmaceutical composition containing the compound, and the use of compound of formula (I) or formula (II) for preventing and/or treating cancer, tumor, inflammatory disease, autoimmune di...

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Hauptverfasser: CHENG Wanli, LI Feifan, YANG Han, HE Nanhai, LIU Canfeng, WU Peng, CHEN Kaixuan, LV Meng, CHEN Yufeng, LIU Shuaishuai
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creator CHENG Wanli
LI Feifan
YANG Han
HE Nanhai
LIU Canfeng
WU Peng
CHEN Kaixuan
LV Meng
CHEN Yufeng
LIU Shuaishuai
description The present invention relates to a pan-KRAS inhibitor compound represented by formula (I) or formula (II) and a pharmaceutical composition containing the compound, and the use of compound of formula (I) or formula (II) for preventing and/or treating cancer, tumor, inflammatory disease, autoimmune disease or immune- mediated disease.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title A pan-KRAS inhibitor compound
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