C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS

Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (C...

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Hauptverfasser: COLANDREA, Vincent J, LI, Yuehu, STRAMBEANU, Iulia, BISHOP, Michael Joseph, STEWART, Eugene L, MCGRANE, Laurel Kathryn, JANETKA, James Walter, WIDDOWSON, Katherine Louisa
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creator COLANDREA, Vincent J
LI, Yuehu
STRAMBEANU, Iulia
BISHOP, Michael Joseph
STEWART, Eugene L
MCGRANE, Laurel Kathryn
JANETKA, James Walter
WIDDOWSON, Katherine Louisa
description Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS
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