C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS
Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (C...
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creator | COLANDREA, Vincent J LI, Yuehu STRAMBEANU, Iulia BISHOP, Michael Joseph STEWART, Eugene L MCGRANE, Laurel Kathryn JANETKA, James Walter WIDDOWSON, Katherine Louisa |
description | Disclosed herein are C-mannoside compounds, compositions thereof and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD). |
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Methods of inhibition of FimH activity in a human subject are also provided for the treatment of diseases such as bacterial infection, Crohn's disease (CD) and Inflammatory Bowel Disease (IBD).</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | C-MANNOSIDE COMPOPUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS |
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