A MODIFIED RAAV CAPSID PROTEIN FOR GENE THERAPY

The invention relates to recombinant adeno-associated virus (rAAV) virions for gene therapy, wherein the rAAV virions comprise a novel capsid protein. In particular, the invention relates to the use of such virions in gene therapy for the treatment of an arthritic disease, such as for example rheuma...

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Hauptverfasser: GRIMM, Dirk, SNOEK, Susanne Anna, BROEKSTRA, Niels, VAN DER SANDEN, Sabine Maria Gertrude, FINN, Jonathan Douglas, BÖRNER, Kathleen
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creator GRIMM, Dirk
SNOEK, Susanne Anna
BROEKSTRA, Niels
VAN DER SANDEN, Sabine Maria Gertrude
FINN, Jonathan Douglas
BÖRNER, Kathleen
description The invention relates to recombinant adeno-associated virus (rAAV) virions for gene therapy, wherein the rAAV virions comprise a novel capsid protein. In particular, the invention relates to the use of such virions in gene therapy for the treatment of an arthritic disease, such as for example rheumatoid arthritis, or symptoms thereof, preferably by intraarticular administration.
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language eng ; lit
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title A MODIFIED RAAV CAPSID PROTEIN FOR GENE THERAPY
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