MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR
Compounds of Formula (I):pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the s...
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| creator | KHATUYA, Haripada MCCARTNEY, Jason TERMIN, Andreas ABELA, Alexander CLEVELAND, Thomas KANG, Ping MILLER, Mark KESHAVARZ-SHOKRI, Ali YOUNG, Tomothy STAVROPOULOS, Kathy ALCACIO, Timothy HADIDA RUAH, Sara KRENITSKY, Paul BAEK, Minson SHI, Yi SHRESTHA, Muna ZHOU, Jinglan ANDERSON, Corey VAN GOOR, Fredrick GROOTENHUIS, Peter Diederik PARASELLI, Prasuna SIESEL, David GROSS, Raymond FERRIS, Lori GULEVICH, Anton HSIA, Clara HUGHES, Robert JOSHI, Pramod UY, Johnny PIERRE, Fabrice Jean CLEMENS, Jeremy ANGELL, Paul |
| description | Compounds of Formula (I):pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof. |
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Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjjEOwjAQBNNQIOAP94BQkAj6i3OOLWI7si8FVRQhUyGIFD7DbzECUVNtM7O7y-xpXN23yM6DkyBOgbUAqSvvgg7AHm0wZKqUBMLZuheMVhB4aj5aDp1Cb1BQn1RsE2W6JLN2NuRgiJWrw7ucPSEbspwD2ho67wSFADJNGzxq2wArgt-fdba4jNc5br65ykASC7WN032I8zSe4y0-hpbL_X53KArm8g_kBYl_Q5Q</recordid><startdate>20210225</startdate><enddate>20210225</enddate><creator>KHATUYA, Haripada</creator><creator>MCCARTNEY, Jason</creator><creator>TERMIN, Andreas</creator><creator>ABELA, Alexander</creator><creator>CLEVELAND, Thomas</creator><creator>KANG, Ping</creator><creator>MILLER, Mark</creator><creator>KESHAVARZ-SHOKRI, Ali</creator><creator>YOUNG, Tomothy</creator><creator>STAVROPOULOS, Kathy</creator><creator>ALCACIO, Timothy</creator><creator>HADIDA RUAH, Sara</creator><creator>KRENITSKY, Paul</creator><creator>BAEK, Minson</creator><creator>SHI, Yi</creator><creator>SHRESTHA, Muna</creator><creator>ZHOU, Jinglan</creator><creator>ANDERSON, Corey</creator><creator>VAN GOOR, Fredrick</creator><creator>GROOTENHUIS, Peter Diederik</creator><creator>PARASELLI, Prasuna</creator><creator>SIESEL, David</creator><creator>GROSS, Raymond</creator><creator>FERRIS, Lori</creator><creator>GULEVICH, Anton</creator><creator>HSIA, Clara</creator><creator>HUGHES, Robert</creator><creator>JOSHI, Pramod</creator><creator>UY, Johnny</creator><creator>PIERRE, Fabrice Jean</creator><creator>CLEMENS, Jeremy</creator><creator>ANGELL, Paul</creator><scope>EVB</scope></search><sort><creationdate>20210225</creationdate><title>MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR</title><author>KHATUYA, Haripada ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR |
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