HPK1 INHIBITORS AND METHODS OF USING SAME

Thienopyridinone compounds of Formula (I) and pharmaceutically acceptable salts thereof are described. In these compounds, one of X1; X2, and X3 is S and the other two are each independently CR, wherein R and all other variables are as defined herein. The compounds are shown to inhibit HPK1 kinase a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	PAULS, Heinz W, LI, Sze-Wan, LAUFER, Radoslaw, LIU, Yong, PATEL, Narendra Kumar B, SAMPSON, Peter Brent, NG, Grace, LANG, Yunhui
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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