POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF
The invention relates medicaments comprising novel polyethylene glycol (PEG) based prodrugs of Adrenomedullin, or one of the salts thereof, solvates thereof or the solvates of salts thereof, in combination with an inert nontoxic pharmaceutically suitable excipient, wherein the medicament is in a pha...
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| creator | KÖLLNBERGER, Maria MARLEY, July KÖBBERLING, Johannes LERCHEN, Hans-Georg WITTROCK, Sven GRIEBENOW, Nils REDLICH, Gorden WUNDER, Frank FLAMME, Ingo KNORR, Andreas PRITCHARD, Iain SCHOHE-LOOP, Rudolf |
| description | The invention relates medicaments comprising novel polyethylene glycol (PEG) based prodrugs of Adrenomedullin, or one of the salts thereof, solvates thereof or the solvates of salts thereof, in combination with an inert nontoxic pharmaceutically suitable excipient, wherein the medicament is in a pharmaceutical form for inhalation, its use for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders, to specific PEG-adrenomedullin prodrugs and its synthesis intermediates. |
| format | Patent |
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MARLEY, July ; KÖBBERLING, Johannes ; LERCHEN, Hans-Georg ; WITTROCK, Sven ; GRIEBENOW, Nils ; REDLICH, Gorden ; WUNDER, Frank ; FLAMME, Ingo ; KNORR, Andreas ; PRITCHARD, Iain ; SCHOHE-LOOP, Rudolf</creatorcontrib><description>The invention relates medicaments comprising novel polyethylene glycol (PEG) based prodrugs of Adrenomedullin, or one of the salts thereof, solvates thereof or the solvates of salts thereof, in combination with an inert nontoxic pharmaceutically suitable excipient, wherein the medicament is in a pharmaceutical form for inhalation, its use for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders, to specific PEG-adrenomedullin prodrugs and its synthesis intermediates.</description><language>eng ; lit</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180226&DB=EPODOC&CC=LT&NR=3075395T$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180226&DB=EPODOC&CC=LT&NR=3075395T$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KÖLLNBERGER, Maria</creatorcontrib><creatorcontrib>MARLEY, July</creatorcontrib><creatorcontrib>KÖBBERLING, Johannes</creatorcontrib><creatorcontrib>LERCHEN, Hans-Georg</creatorcontrib><creatorcontrib>WITTROCK, Sven</creatorcontrib><creatorcontrib>GRIEBENOW, Nils</creatorcontrib><creatorcontrib>REDLICH, Gorden</creatorcontrib><creatorcontrib>WUNDER, Frank</creatorcontrib><creatorcontrib>FLAMME, Ingo</creatorcontrib><creatorcontrib>KNORR, Andreas</creatorcontrib><creatorcontrib>PRITCHARD, Iain</creatorcontrib><creatorcontrib>SCHOHE-LOOP, Rudolf</creatorcontrib><title>POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF</title><description>The invention relates medicaments comprising novel polyethylene glycol (PEG) based prodrugs of Adrenomedullin, or one of the salts thereof, solvates thereof or the solvates of salts thereof, in combination with an inert nontoxic pharmaceutically suitable excipient, wherein the medicament is in a pharmaceutical form for inhalation, its use for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders, to specific PEG-adrenomedullin prodrugs and its synthesis intermediates.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAO8PeJdA3xiPRx9XNVcPeJdPb3UXByDHZ1UQgI8ncJCnVX8HdTcHQJcvXz93V1CfXx8fRTcPRzUQgNdlUI8XANcvV342FgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8T4hxgbmpsaWpiEhxkQoAQD2TCu3</recordid><startdate>20180226</startdate><enddate>20180226</enddate><creator>KÖLLNBERGER, Maria</creator><creator>MARLEY, July</creator><creator>KÖBBERLING, Johannes</creator><creator>LERCHEN, Hans-Georg</creator><creator>WITTROCK, Sven</creator><creator>GRIEBENOW, Nils</creator><creator>REDLICH, Gorden</creator><creator>WUNDER, Frank</creator><creator>FLAMME, Ingo</creator><creator>KNORR, Andreas</creator><creator>PRITCHARD, Iain</creator><creator>SCHOHE-LOOP, Rudolf</creator><scope>EVB</scope></search><sort><creationdate>20180226</creationdate><title>POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF</title><author>KÖLLNBERGER, Maria ; 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| language | eng ; lit |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF |
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