3,4-DIHYDROISOQUINOLIN-2(1H)-YL COMPOUNDS

3,4-DIHYDROISOQUINOLIN-2(1H)-YL COMPOUNDS

The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula I, and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I to treat cognitive impairment associated with Parkinson's disease or sc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: COATES, David Andrew, REINHARD, Matthew Robert, BEADLE, Christopher David, SCHAUS, John Mehnert, WOLFANGEL, Craig Daniel, HAO, Junliang, KRUSHINSKI JR., Joseph Herman
Format: Patent
Sprache:eng ; lit
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula I, and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I to treat cognitive impairment associated with Parkinson's disease or schizophrenia.