PROCESS FOR PREPARING BENZOXAZOLINONES

The invention relates to compounds of the formula: in which R represents hydrogen or a lower alkyl radical and R1 and R2 separately represent hydrogen, a lower alkyl, cycloalkyl or benzyl radical, or represent, together with the nitrogen atom to which they are bonded, a heterocyclic radical such as...

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Hauptverfasser: LESIEUR, DANIEL, BUSCH, NORBERT, CAIGNARD, DANIEL H, LESPAGNOL, CHARLES
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Sprache:eng ; kor
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creator LESIEUR, DANIEL
BUSCH, NORBERT
CAIGNARD, DANIEL H
LESPAGNOL, CHARLES
description The invention relates to compounds of the formula: in which R represents hydrogen or a lower alkyl radical and R1 and R2 separately represent hydrogen, a lower alkyl, cycloalkyl or benzyl radical, or represent, together with the nitrogen atom to which they are bonded, a heterocyclic radical such as a morpholino, 4-(pyrimidin-2-yl)-piperazinyl or 4-phenylpiperazinyl the phenyl radical of which being optionally substituted by halogen, lower alkoxy or trifluoromethyl, having CNS activity and particularly hypnotic properties. Moreover the compounds in which R1 and R2 are hydrogen can be used in the treatment of heart failure.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR PREPARING BENZOXAZOLINONES
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