PROCESS FOR PREPARING SUBSTITUTED WAROYE(PROPIONYL OR BUTYRYL)-L-PROLINES

Title compds. I (R3=mercapto, formylthio, benzoylthio, C2˜C4 alkanoylthio; R4=H, Ph, C1˜C4 alkyl; R5=H C1˜C4 alkyl)were prepd. as hypotensives; they inhibited angiotensinconverting enzyme (ACE). Thus, 165mL dioxane soln. contg. 26.4g benzoyl acrylate and 17.25g N-hydroxysuccinimide was treated with...

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Bibliographische Detailangaben
Hauptverfasser: MCEVOY FRANCIS JOSEPH, ALBRIGHT JAY DONALD
Format: Patent
Sprache:eng
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