PROCESS FOR PREPAING PYRAZINE DERIVATIVES

PROCESS FOR PREPAING PYRAZINE DERIVATIVES

Pyrazine deriv. [I; R1,R2 = H, halogen, hydroxy group, phenyl lower alkoxy group, phenoxy group, mercapto group, phenyl lower alkylthio group, amino group, carbamoyl group, or sulfamoyl group, R3= lower alkoxy group, R4,R5,R6= H, lower alkyl group, cycloalkyl group, or phenyl group, A= lower alkyl g...

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Hauptverfasser: YASUHUMI HIRATA, MUTSUO TAKASHIMO, MASUO MARAKAMI, HIROYOSHI INO, MASAAKI TAKEDA, KOZO TAKAHASHI
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creator YASUHUMI HIRATA
MUTSUO TAKASHIMO
MASUO MARAKAMI
HIROYOSHI INO
MASAAKI TAKEDA
KOZO TAKAHASHI
description Pyrazine deriv. [I; R1,R2 = H, halogen, hydroxy group, phenyl lower alkoxy group, phenoxy group, mercapto group, phenyl lower alkylthio group, amino group, carbamoyl group, or sulfamoyl group, R3= lower alkoxy group, R4,R5,R6= H, lower alkyl group, cycloalkyl group, or phenyl group, A= lower alkyl group , useful as antiemetic, were prepd. by reaction of pyrazine carboxylic acid (II) or its deriv. with amino deriv. (III).
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title PROCESS FOR PREPAING PYRAZINE DERIVATIVES
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