다형성 화합물 및 이의 용도
본 발명은 CDK4 및 CDK6의 억제제로서 작용하는 소분자 치료제를 투여하여 암과 같은 다양한 CDK4-매개 장애 및 CDK6-매개 장애를 치료하는 데 유용한 유리염기 및 염 형태를 제공한다. 유리염기 및 염 형태를 포함하는 약학적 조성물뿐만 아니라 이의 사용 및 제조 방법이 또한 기술된다. The present invention provides freebase and salt forms useful for treating various CDK4-mediated and a CDK6-mediated disorders, such as...
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| creator | SHEN BO DAI CHAOFENG WEI YUFENG YE PENGPENG BUESKING ANDREW WEN SAISHUAI SATHYANARAYANA REDDY PERUMALLA CAO GANFENG COMBS ANDREW |
| description | 본 발명은 CDK4 및 CDK6의 억제제로서 작용하는 소분자 치료제를 투여하여 암과 같은 다양한 CDK4-매개 장애 및 CDK6-매개 장애를 치료하는 데 유용한 유리염기 및 염 형태를 제공한다. 유리염기 및 염 형태를 포함하는 약학적 조성물뿐만 아니라 이의 사용 및 제조 방법이 또한 기술된다.
The present invention provides freebase and salt forms useful for treating various CDK4-mediated and a CDK6-mediated disorders, such as cancer, by the administration of small molecule therapeutics that act as inhibitors of CDK4 and CDK6. Pharmaceutical compositions comprising the freebase and salt forms, as well as methods of their use and preparation, are also described. |
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The present invention provides freebase and salt forms useful for treating various CDK4-mediated and a CDK6-mediated disorders, such as cancer, by the administration of small molecule therapeutics that act as inhibitors of CDK4 and CDK6. Pharmaceutical compositions comprising the freebase and salt forms, as well as methods of their use and preparation, are also described.</description><language>kor</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241126&DB=EPODOC&CC=KR&NR=20240166545A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241126&DB=EPODOC&CC=KR&NR=20240166545A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHEN BO</creatorcontrib><creatorcontrib>DAI CHAOFENG</creatorcontrib><creatorcontrib>WEI YUFENG</creatorcontrib><creatorcontrib>YE PENGPENG</creatorcontrib><creatorcontrib>BUESKING ANDREW</creatorcontrib><creatorcontrib>WEN SAISHUAI</creatorcontrib><creatorcontrib>SATHYANARAYANA REDDY PERUMALLA</creatorcontrib><creatorcontrib>CAO GANFENG</creatorcontrib><creatorcontrib>COMBS ANDREW</creatorcontrib><title>다형성 화합물 및 이의 용도</title><description>본 발명은 CDK4 및 CDK6의 억제제로서 작용하는 소분자 치료제를 투여하여 암과 같은 다양한 CDK4-매개 장애 및 CDK6-매개 장애를 치료하는 데 유용한 유리염기 및 염 형태를 제공한다. 유리염기 및 염 형태를 포함하는 약학적 조성물뿐만 아니라 이의 사용 및 제조 방법이 또한 기술된다.
The present invention provides freebase and salt forms useful for treating various CDK4-mediated and a CDK6-mediated disorders, such as cancer, by the administration of small molecule therapeutics that act as inhibitors of CDK4 and CDK6. Pharmaceutical compositions comprising the freebase and salt forms, as well as methods of their use and preparation, are also described.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB93b3k7Yypb1o2KrydOeXt1JWv1-xReL2hX-HN3C1v5s5QeDNr5ev-Fh4G1rTEnOJUXijNzaDs5hri7KGbWpAfn1pckJicmpdaEu8dZGRgZGJgaGZmamLqaEycKgA85DIQ</recordid><startdate>20241126</startdate><enddate>20241126</enddate><creator>SHEN BO</creator><creator>DAI CHAOFENG</creator><creator>WEI YUFENG</creator><creator>YE PENGPENG</creator><creator>BUESKING ANDREW</creator><creator>WEN SAISHUAI</creator><creator>SATHYANARAYANA REDDY PERUMALLA</creator><creator>CAO GANFENG</creator><creator>COMBS ANDREW</creator><scope>EVB</scope></search><sort><creationdate>20241126</creationdate><title>다형성 화합물 및 이의 용도</title><author>SHEN BO ; DAI CHAOFENG ; WEI YUFENG ; YE PENGPENG ; BUESKING ANDREW ; WEN SAISHUAI ; SATHYANARAYANA REDDY PERUMALLA ; CAO GANFENG ; COMBS ANDREW</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20240166545A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2024</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SHEN BO</creatorcontrib><creatorcontrib>DAI CHAOFENG</creatorcontrib><creatorcontrib>WEI YUFENG</creatorcontrib><creatorcontrib>YE PENGPENG</creatorcontrib><creatorcontrib>BUESKING ANDREW</creatorcontrib><creatorcontrib>WEN SAISHUAI</creatorcontrib><creatorcontrib>SATHYANARAYANA REDDY PERUMALLA</creatorcontrib><creatorcontrib>CAO GANFENG</creatorcontrib><creatorcontrib>COMBS ANDREW</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHEN BO</au><au>DAI CHAOFENG</au><au>WEI YUFENG</au><au>YE PENGPENG</au><au>BUESKING ANDREW</au><au>WEN SAISHUAI</au><au>SATHYANARAYANA REDDY PERUMALLA</au><au>CAO GANFENG</au><au>COMBS ANDREW</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>다형성 화합물 및 이의 용도</title><date>2024-11-26</date><risdate>2024</risdate><abstract>본 발명은 CDK4 및 CDK6의 억제제로서 작용하는 소분자 치료제를 투여하여 암과 같은 다양한 CDK4-매개 장애 및 CDK6-매개 장애를 치료하는 데 유용한 유리염기 및 염 형태를 제공한다. 유리염기 및 염 형태를 포함하는 약학적 조성물뿐만 아니라 이의 사용 및 제조 방법이 또한 기술된다.
The present invention provides freebase and salt forms useful for treating various CDK4-mediated and a CDK6-mediated disorders, such as cancer, by the administration of small molecule therapeutics that act as inhibitors of CDK4 and CDK6. Pharmaceutical compositions comprising the freebase and salt forms, as well as methods of their use and preparation, are also described.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 다형성 화합물 및 이의 용도 |
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