항-GD2 항체, 면역접합체 및 그의 치료적 용도
본 발명은 인간 GD2 단백질에 결합하는 항체, 뿐만 아니라 상기 항체를 코딩하는 서열을 포함하는 단리된 핵산 및 숙주 세포를 제공한다. 본 발명은 또한 성장 억제제에 연결된 상기 항체를 포함하는 면역접합체, 및 본 발명의 항체 또는 면역접합체를 포함하는 제약 조성물을 제공한다. 본 발명은 또한 암 치료 또는 진단 목적을 위한 본 발명의 항체, 면역접합체 및 제약 조성물의 용도를 제공한다. The invention provides antibodies which bind human GD2 protein, as well as isola...
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| creator | SLOOT WILLEM GROSS ALEC MA JIANGUO ANDERL JAN RASCHE NICOLAS DOTTERWEICH JULIA SHAN MIN AMENDT CHRISTIANE MCKENNA SEAN D |
| description | 본 발명은 인간 GD2 단백질에 결합하는 항체, 뿐만 아니라 상기 항체를 코딩하는 서열을 포함하는 단리된 핵산 및 숙주 세포를 제공한다. 본 발명은 또한 성장 억제제에 연결된 상기 항체를 포함하는 면역접합체, 및 본 발명의 항체 또는 면역접합체를 포함하는 제약 조성물을 제공한다. 본 발명은 또한 암 치료 또는 진단 목적을 위한 본 발명의 항체, 면역접합체 및 제약 조성물의 용도를 제공한다.
The invention provides antibodies which bind human GD2 protein, as well as isolated nucleic acids and host cells comprising a sequence encoding said antibodies. The invention also provides immunoconjugates comprising said antibodies linked to a growth-inhibitory agent, and pharmaceutical compositions comprising antibodies or immunoconjugates of the invention. The invention also provides use of the antibodies, immunoconjugates and pharmaceutical compositions of the invention for the treatment of cancer or for diagnostic purposes. |
| format | Patent |
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The invention provides antibodies which bind human GD2 protein, as well as isolated nucleic acids and host cells comprising a sequence encoding said antibodies. The invention also provides immunoconjugates comprising said antibodies linked to a growth-inhibitory agent, and pharmaceutical compositions comprising antibodies or immunoconjugates of the invention. The invention also provides use of the antibodies, immunoconjugates and pharmaceutical compositions of the invention for the treatment of cancer or for diagnostic purposes.</description><language>kor</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241028&DB=EPODOC&CC=KR&NR=20240155334A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241028&DB=EPODOC&CC=KR&NR=20240155334A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SLOOT WILLEM</creatorcontrib><creatorcontrib>GROSS ALEC</creatorcontrib><creatorcontrib>MA JIANGUO</creatorcontrib><creatorcontrib>ANDERL JAN</creatorcontrib><creatorcontrib>RASCHE NICOLAS</creatorcontrib><creatorcontrib>DOTTERWEICH JULIA</creatorcontrib><creatorcontrib>SHAN MIN</creatorcontrib><creatorcontrib>AMENDT CHRISTIANE</creatorcontrib><creatorcontrib>MCKENNA SEAN D</creatorcontrib><title>항-GD2 항체, 면역접합체 및 그의 치료적 용도</title><description>본 발명은 인간 GD2 단백질에 결합하는 항체, 뿐만 아니라 상기 항체를 코딩하는 서열을 포함하는 단리된 핵산 및 숙주 세포를 제공한다. 본 발명은 또한 성장 억제제에 연결된 상기 항체를 포함하는 면역접합체, 및 본 발명의 항체 또는 면역접합체를 포함하는 제약 조성물을 제공한다. 본 발명은 또한 암 치료 또는 진단 목적을 위한 본 발명의 항체, 면역접합체 및 제약 조성물의 용도를 제공한다.
The invention provides antibodies which bind human GD2 protein, as well as isolated nucleic acids and host cells comprising a sequence encoding said antibodies. The invention also provides immunoconjugates comprising said antibodies linked to a growth-inhibitory agent, and pharmaceutical compositions comprising antibodies or immunoconjugates of the invention. The invention also provides use of the antibodies, immunoconjugates and pharmaceutical compositions of the invention for the treatment of cancer or for diagnostic purposes.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB-O3WtrruLkQKQfrNpi47C65Vb3kxf-2bBxLdTVwIFFF5v6Fd4tX3Hm7kzFN7snPF6cc-bBY0Kb2atfN3fwsPAmpaYU5zKC6W5GZTdXEOcPXRTC_LjU4sLEpNT81JL4r2DjAyMTAwMTU2NjU0cjYlTBQAzMT7F</recordid><startdate>20241028</startdate><enddate>20241028</enddate><creator>SLOOT WILLEM</creator><creator>GROSS ALEC</creator><creator>MA JIANGUO</creator><creator>ANDERL JAN</creator><creator>RASCHE NICOLAS</creator><creator>DOTTERWEICH JULIA</creator><creator>SHAN MIN</creator><creator>AMENDT CHRISTIANE</creator><creator>MCKENNA SEAN D</creator><scope>EVB</scope></search><sort><creationdate>20241028</creationdate><title>항-GD2 항체, 면역접합체 및 그의 치료적 용도</title><author>SLOOT WILLEM ; GROSS ALEC ; MA JIANGUO ; ANDERL JAN ; RASCHE NICOLAS ; DOTTERWEICH JULIA ; SHAN MIN ; AMENDT CHRISTIANE ; MCKENNA SEAN D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20240155334A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SLOOT WILLEM</creatorcontrib><creatorcontrib>GROSS ALEC</creatorcontrib><creatorcontrib>MA JIANGUO</creatorcontrib><creatorcontrib>ANDERL JAN</creatorcontrib><creatorcontrib>RASCHE NICOLAS</creatorcontrib><creatorcontrib>DOTTERWEICH JULIA</creatorcontrib><creatorcontrib>SHAN MIN</creatorcontrib><creatorcontrib>AMENDT CHRISTIANE</creatorcontrib><creatorcontrib>MCKENNA SEAN D</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SLOOT WILLEM</au><au>GROSS ALEC</au><au>MA JIANGUO</au><au>ANDERL JAN</au><au>RASCHE NICOLAS</au><au>DOTTERWEICH JULIA</au><au>SHAN MIN</au><au>AMENDT CHRISTIANE</au><au>MCKENNA SEAN D</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>항-GD2 항체, 면역접합체 및 그의 치료적 용도</title><date>2024-10-28</date><risdate>2024</risdate><abstract>본 발명은 인간 GD2 단백질에 결합하는 항체, 뿐만 아니라 상기 항체를 코딩하는 서열을 포함하는 단리된 핵산 및 숙주 세포를 제공한다. 본 발명은 또한 성장 억제제에 연결된 상기 항체를 포함하는 면역접합체, 및 본 발명의 항체 또는 면역접합체를 포함하는 제약 조성물을 제공한다. 본 발명은 또한 암 치료 또는 진단 목적을 위한 본 발명의 항체, 면역접합체 및 제약 조성물의 용도를 제공한다.
The invention provides antibodies which bind human GD2 protein, as well as isolated nucleic acids and host cells comprising a sequence encoding said antibodies. The invention also provides immunoconjugates comprising said antibodies linked to a growth-inhibitory agent, and pharmaceutical compositions comprising antibodies or immunoconjugates of the invention. The invention also provides use of the antibodies, immunoconjugates and pharmaceutical compositions of the invention for the treatment of cancer or for diagnostic purposes.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 항-GD2 항체, 면역접합체 및 그의 치료적 용도 |
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