SETDB1 NOVEL COMPOUNDS WITH SETDB1 INHIBITORY ACTIVITY AND USE THEREOF
본 발명은 히스톤 H3K9에 특이적인 히스톤 메틸기전이효소인 SETDB1의 억제 활성을 갖는 신규한 화합물 및 이의 용도를 제공한다. 또한, 본 발명에 따른 신규한 화합물들은 SETDB1관련 질환, 바람직하게는 SETDB1의 기능 이상과 연관된 암의 예방 또는 치료에 유용하게 사용될 수 있다. The present invention provides a novel compound exhibiting the inhibitory activity of SETDB1, which is a histone methyltransferase spec...
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| creator | MOON HYUNG JO SHIN JAE HONG KANG JU HEE HWANG JAE SUNG |
| description | 본 발명은 히스톤 H3K9에 특이적인 히스톤 메틸기전이효소인 SETDB1의 억제 활성을 갖는 신규한 화합물 및 이의 용도를 제공한다. 또한, 본 발명에 따른 신규한 화합물들은 SETDB1관련 질환, 바람직하게는 SETDB1의 기능 이상과 연관된 암의 예방 또는 치료에 유용하게 사용될 수 있다.
The present invention provides a novel compound exhibiting the inhibitory activity of SETDB1, which is a histone methyltransferase specific to histone H3K9, and use thereof. In addition, the novel compounds according to the prevent invention can be effectively used for preventing or treating SETDB1-associated disease, particularly, cancer associated with SETDB1 dysfunction. |
| format | Patent |
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The present invention provides a novel compound exhibiting the inhibitory activity of SETDB1, which is a histone methyltransferase specific to histone H3K9, and use thereof. In addition, the novel compounds according to the prevent invention can be effectively used for preventing or treating SETDB1-associated disease, particularly, cancer associated with SETDB1 dysfunction.</description><language>eng ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241028&DB=EPODOC&CC=KR&NR=20240154714A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241028&DB=EPODOC&CC=KR&NR=20240154714A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOON HYUNG JO</creatorcontrib><creatorcontrib>SHIN JAE HONG</creatorcontrib><creatorcontrib>KANG JU HEE</creatorcontrib><creatorcontrib>HWANG JAE SUNG</creatorcontrib><title>SETDB1 NOVEL COMPOUNDS WITH SETDB1 INHIBITORY ACTIVITY AND USE THEREOF</title><description>본 발명은 히스톤 H3K9에 특이적인 히스톤 메틸기전이효소인 SETDB1의 억제 활성을 갖는 신규한 화합물 및 이의 용도를 제공한다. 또한, 본 발명에 따른 신규한 화합물들은 SETDB1관련 질환, 바람직하게는 SETDB1의 기능 이상과 연관된 암의 예방 또는 치료에 유용하게 사용될 수 있다.
The present invention provides a novel compound exhibiting the inhibitory activity of SETDB1, which is a histone methyltransferase specific to histone H3K9, and use thereof. In addition, the novel compounds according to the prevent invention can be effectively used for preventing or treating SETDB1-associated disease, particularly, cancer associated with SETDB1 dysfunction.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHALdg1xcTJU8PMPc_VRcPb3DfAP9XMJVgj3DPFQgMp5-nl4OnmG-AdFKjg6h3iGeYYAGX4uCqHBrgohHq5Brv5uPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7Uk3jvIyMDIxMDQ1MTc0MTRmDhVAFmhLR4</recordid><startdate>20241028</startdate><enddate>20241028</enddate><creator>MOON HYUNG JO</creator><creator>SHIN JAE HONG</creator><creator>KANG JU HEE</creator><creator>HWANG JAE SUNG</creator><scope>EVB</scope></search><sort><creationdate>20241028</creationdate><title>SETDB1 NOVEL COMPOUNDS WITH SETDB1 INHIBITORY ACTIVITY AND USE THEREOF</title><author>MOON HYUNG JO ; SHIN JAE HONG ; KANG JU HEE ; HWANG JAE SUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20240154714A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MOON HYUNG JO</creatorcontrib><creatorcontrib>SHIN JAE HONG</creatorcontrib><creatorcontrib>KANG JU HEE</creatorcontrib><creatorcontrib>HWANG JAE SUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MOON HYUNG JO</au><au>SHIN JAE HONG</au><au>KANG JU HEE</au><au>HWANG JAE SUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SETDB1 NOVEL COMPOUNDS WITH SETDB1 INHIBITORY ACTIVITY AND USE THEREOF</title><date>2024-10-28</date><risdate>2024</risdate><abstract>본 발명은 히스톤 H3K9에 특이적인 히스톤 메틸기전이효소인 SETDB1의 억제 활성을 갖는 신규한 화합물 및 이의 용도를 제공한다. 또한, 본 발명에 따른 신규한 화합물들은 SETDB1관련 질환, 바람직하게는 SETDB1의 기능 이상과 연관된 암의 예방 또는 치료에 유용하게 사용될 수 있다.
The present invention provides a novel compound exhibiting the inhibitory activity of SETDB1, which is a histone methyltransferase specific to histone H3K9, and use thereof. In addition, the novel compounds according to the prevent invention can be effectively used for preventing or treating SETDB1-associated disease, particularly, cancer associated with SETDB1 dysfunction.</abstract><oa>free_for_read</oa></addata></record> |
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| title | SETDB1 NOVEL COMPOUNDS WITH SETDB1 INHIBITORY ACTIVITY AND USE THEREOF |
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