혈액암에 대한 LAG-3 길항제 요법
본 개시내용은 혈액암을 앓는 인간 대상체를 림프구 활성화 유전자-3 (LAG-3) 길항제로 치료하는 방법을 제공한다. 일부 측면에서, 방법은 LAG-3 길항제와 추가의 치료제 (예를 들어, 프로그램화된 사멸-1 경로 억제제)의 조합을 포함한다. 일부 측면에서, 대상체는 약 12세 이상이고, 약 40 kg 이상의 체중을 가지며, 약 30세 이하 또는 약 18세 미만의 대상체를 포함한다. 일부 측면에서, 대상체는 약 40 kg 미만의 체중을 갖고/거나 약 12세 미만이다. The disclosure provides a method of...
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creator | CHEONG ALICIA MUN YEN SRIVASTAVA SHIVANI GELB ARNOLD BRUCE AGRAWAL SHRUTIDEVI KUNJBIHARILAL |
description | 본 개시내용은 혈액암을 앓는 인간 대상체를 림프구 활성화 유전자-3 (LAG-3) 길항제로 치료하는 방법을 제공한다. 일부 측면에서, 방법은 LAG-3 길항제와 추가의 치료제 (예를 들어, 프로그램화된 사멸-1 경로 억제제)의 조합을 포함한다. 일부 측면에서, 대상체는 약 12세 이상이고, 약 40 kg 이상의 체중을 가지며, 약 30세 이하 또는 약 18세 미만의 대상체를 포함한다. 일부 측면에서, 대상체는 약 40 kg 미만의 체중을 갖고/거나 약 12세 미만이다.
The disclosure provides a method of treating a human subject afflicted with a hematological cancer with a lymphocyte activation gene-3 (LAG-3) antagonist. In some aspects, the method comprises combination of the LAG-3 antagonist with an additional therapeutic agent (e.g., a programmed death-1 pathway inhibitor). In some aspects, the subject is greater than or equal to about 12 years old and has a weight of greater than or equal to about 40 kg, including subjects less than or equal to about 30 years old or less than about 18 years old. In some aspects, the subject has a weight of less than about 40 kg and/or is less than about 12 years old. |
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The disclosure provides a method of treating a human subject afflicted with a hematological cancer with a lymphocyte activation gene-3 (LAG-3) antagonist. In some aspects, the method comprises combination of the LAG-3 antagonist with an additional therapeutic agent (e.g., a programmed death-1 pathway inhibitor). In some aspects, the subject is greater than or equal to about 12 years old and has a weight of greater than or equal to about 40 kg, including subjects less than or equal to about 30 years old or less than about 18 years old. In some aspects, the subject has a weight of less than about 40 kg and/or is less than about 12 years old.</description><language>kor</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240628&DB=EPODOC&CC=KR&NR=20240099362A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240628&DB=EPODOC&CC=KR&NR=20240099362A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEONG ALICIA MUN YEN</creatorcontrib><creatorcontrib>SRIVASTAVA SHIVANI</creatorcontrib><creatorcontrib>GELB ARNOLD BRUCE</creatorcontrib><creatorcontrib>AGRAWAL SHRUTIDEVI KUNJBIHARILAL</creatorcontrib><title>혈액암에 대한 LAG-3 길항제 요법</title><description>본 개시내용은 혈액암을 앓는 인간 대상체를 림프구 활성화 유전자-3 (LAG-3) 길항제로 치료하는 방법을 제공한다. 일부 측면에서, 방법은 LAG-3 길항제와 추가의 치료제 (예를 들어, 프로그램화된 사멸-1 경로 억제제)의 조합을 포함한다. 일부 측면에서, 대상체는 약 12세 이상이고, 약 40 kg 이상의 체중을 가지며, 약 30세 이하 또는 약 18세 미만의 대상체를 포함한다. 일부 측면에서, 대상체는 약 40 kg 미만의 체중을 갖고/거나 약 12세 미만이다.
The disclosure provides a method of treating a human subject afflicted with a hematological cancer with a lymphocyte activation gene-3 (LAG-3) antagonist. In some aspects, the method comprises combination of the LAG-3 antagonist with an additional therapeutic agent (e.g., a programmed death-1 pathway inhibitor). In some aspects, the subject is greater than or equal to about 12 years old and has a weight of greater than or equal to about 40 kg, including subjects less than or equal to about 30 years old or less than about 18 years old. In some aspects, the subject has a weight of less than about 40 kg and/or is less than about 12 years old.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB6O6PjzdSFb6ZOeTN9gsLrnoa3U-co-Di66xorvNqx4-3UtW8WzFF4M2vK601TeRhY0xJzilN5oTQ3g7Kba4izh25qQX58anFBYnJqXmpJvHeQkYGRiYGBpaWxmZGjMXGqAOm5MxQ</recordid><startdate>20240628</startdate><enddate>20240628</enddate><creator>CHEONG ALICIA MUN YEN</creator><creator>SRIVASTAVA SHIVANI</creator><creator>GELB ARNOLD BRUCE</creator><creator>AGRAWAL SHRUTIDEVI KUNJBIHARILAL</creator><scope>EVB</scope></search><sort><creationdate>20240628</creationdate><title>혈액암에 대한 LAG-3 길항제 요법</title><author>CHEONG ALICIA MUN YEN ; SRIVASTAVA SHIVANI ; GELB ARNOLD BRUCE ; AGRAWAL SHRUTIDEVI KUNJBIHARILAL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20240099362A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>kor</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEONG ALICIA MUN YEN</creatorcontrib><creatorcontrib>SRIVASTAVA SHIVANI</creatorcontrib><creatorcontrib>GELB ARNOLD BRUCE</creatorcontrib><creatorcontrib>AGRAWAL SHRUTIDEVI KUNJBIHARILAL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEONG ALICIA MUN YEN</au><au>SRIVASTAVA SHIVANI</au><au>GELB ARNOLD BRUCE</au><au>AGRAWAL SHRUTIDEVI KUNJBIHARILAL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>혈액암에 대한 LAG-3 길항제 요법</title><date>2024-06-28</date><risdate>2024</risdate><abstract>본 개시내용은 혈액암을 앓는 인간 대상체를 림프구 활성화 유전자-3 (LAG-3) 길항제로 치료하는 방법을 제공한다. 일부 측면에서, 방법은 LAG-3 길항제와 추가의 치료제 (예를 들어, 프로그램화된 사멸-1 경로 억제제)의 조합을 포함한다. 일부 측면에서, 대상체는 약 12세 이상이고, 약 40 kg 이상의 체중을 가지며, 약 30세 이하 또는 약 18세 미만의 대상체를 포함한다. 일부 측면에서, 대상체는 약 40 kg 미만의 체중을 갖고/거나 약 12세 미만이다.
The disclosure provides a method of treating a human subject afflicted with a hematological cancer with a lymphocyte activation gene-3 (LAG-3) antagonist. In some aspects, the method comprises combination of the LAG-3 antagonist with an additional therapeutic agent (e.g., a programmed death-1 pathway inhibitor). In some aspects, the subject is greater than or equal to about 12 years old and has a weight of greater than or equal to about 40 kg, including subjects less than or equal to about 30 years old or less than about 18 years old. In some aspects, the subject has a weight of less than about 40 kg and/or is less than about 12 years old.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 혈액암에 대한 LAG-3 길항제 요법 |
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