Methanotroph with improved ectoine productivity through deletion of ectoine hydrolase gene and method of producing ectoine using thereof

Methanotroph with improved ectoine productivity through deletion of ectoine hydrolase gene and method of producing ectoine using thereof

본 발명은 엑토인 생산 능력이 우수한 메탄자화균 및 이를 이용하여 엑토인을 생산하는 방법에 관한 것으로, 본 발명에 따라 엑토인 가수분해효소 유전자의 전부 또는 일부가 결실된 메탄자화균 균주를 구리 공급원 및 질소 공급원의 농도가 최적화된 배지에서 유가식 배양함으로써 종래의 메탄자화균을 회분식 배양하는 방법보다 약 12배 이상 증가된 수치의 효과적인 엑토인 생산이 가능하다....

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Hauptverfasser: LIM SANG EUN, LEE JINWON, CHO SUKHYEONG, NA JEONG GEOL
Format: Patent
Sprache:eng ; kor
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BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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creator LIM SANG EUN
LEE JINWON
CHO SUKHYEONG
NA JEONG GEOL
description 본 발명은 엑토인 생산 능력이 우수한 메탄자화균 및 이를 이용하여 엑토인을 생산하는 방법에 관한 것으로, 본 발명에 따라 엑토인 가수분해효소 유전자의 전부 또는 일부가 결실된 메탄자화균 균주를 구리 공급원 및 질소 공급원의 농도가 최적화된 배지에서 유가식 배양함으로써 종래의 메탄자화균을 회분식 배양하는 방법보다 약 12배 이상 증가된 수치의 효과적인 엑토인 생산이 가능하다.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Methanotroph with improved ectoine productivity through deletion of ectoine hydrolase gene and method of producing ectoine using thereof
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