Pharmaceutical composition for preventing or treating diseases caused by vascular aging comprising Salvia miltiorrhiza extract or Paeonia lactiflora extract as an active ingredient
본 발명은 단삼(Salvia miltiorrhiza) 또는 작약(Paeonialactiflora) 추출물을 유효성분으로 포함하는 혈관 노화로 유발되는 질환 예방 또는 치료용 약학 조성물에 관한 것으로, 단삼 및 작약 각각의 단독 추출물 또는 특정 중량비율로 혼합한 혼합 추출물이 혈관 노화에 의한 세포독성에 대한 세포 보호, 산화질소(nitric oxide) 생성 촉진, 콜라겐(collagen) 섬유 생성 억제, 혈관 두께 증가 억제 및 콜라겐 침착에 의한 섬유도 억제 활성과 같은 혈관 노화에 의한 증상 개선 효과를 나타내는 것을 확...
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| creator | SONG SUKJIN CHA JINWOOK BANG SANGWOO SON JUAH CHA MI RAN OH BYULNIM |
| description | 본 발명은 단삼(Salvia miltiorrhiza) 또는 작약(Paeonialactiflora) 추출물을 유효성분으로 포함하는 혈관 노화로 유발되는 질환 예방 또는 치료용 약학 조성물에 관한 것으로, 단삼 및 작약 각각의 단독 추출물 또는 특정 중량비율로 혼합한 혼합 추출물이 혈관 노화에 의한 세포독성에 대한 세포 보호, 산화질소(nitric oxide) 생성 촉진, 콜라겐(collagen) 섬유 생성 억제, 혈관 두께 증가 억제 및 콜라겐 침착에 의한 섬유도 억제 활성과 같은 혈관 노화에 의한 증상 개선 효과를 나타내는 것을 확인함으로써, 혈관 노화로 유발되는 질환이나 증상의 예방, 치료 또는 개선용 조성물로서 유용하게 활용될 수 있다.
The present disclosure relates to a pharmaceutical composition for preventing or treating diseases caused by vascular aging, including a Salvia miltiorrhiza extract or a Paeonia lactiflora extract as an active ingredient, wherein it was found that a single extract of each of Salvia miltiorrhiza and Paeonia lactiflora or a mixed extract of both mixed in a specific weight ratio showed effects of improving symptoms by vascular aging such as cytoprotection against cytotoxicity due to vascular aging, promotion of nitric oxide production, inhibition of collagen fiber production, suppression of vascular thickness increase, and inhibitory activities on fibrosis by collagen deposition, thereby being useful as a composition for preventing, treating, or ameliorating diseases or symptoms caused by vascular aging. |
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The present disclosure relates to a pharmaceutical composition for preventing or treating diseases caused by vascular aging, including a Salvia miltiorrhiza extract or a Paeonia lactiflora extract as an active ingredient, wherein it was found that a single extract of each of Salvia miltiorrhiza and Paeonia lactiflora or a mixed extract of both mixed in a specific weight ratio showed effects of improving symptoms by vascular aging such as cytoprotection against cytotoxicity due to vascular aging, promotion of nitric oxide production, inhibition of collagen fiber production, suppression of vascular thickness increase, and inhibitory activities on fibrosis by collagen deposition, thereby being useful as a composition for preventing, treating, or ameliorating diseases or symptoms caused by vascular aging.</description><language>eng ; kor</language><subject>FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240514&DB=EPODOC&CC=KR&NR=20240065602A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240514&DB=EPODOC&CC=KR&NR=20240065602A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SONG SUKJIN</creatorcontrib><creatorcontrib>CHA JINWOOK</creatorcontrib><creatorcontrib>BANG SANGWOO</creatorcontrib><creatorcontrib>SON JUAH</creatorcontrib><creatorcontrib>CHA MI RAN</creatorcontrib><creatorcontrib>OH BYULNIM</creatorcontrib><title>Pharmaceutical composition for preventing or treating diseases caused by vascular aging comprising Salvia miltiorrhiza extract or Paeonia lactiflora extract as an active ingredient</title><description>본 발명은 단삼(Salvia miltiorrhiza) 또는 작약(Paeonialactiflora) 추출물을 유효성분으로 포함하는 혈관 노화로 유발되는 질환 예방 또는 치료용 약학 조성물에 관한 것으로, 단삼 및 작약 각각의 단독 추출물 또는 특정 중량비율로 혼합한 혼합 추출물이 혈관 노화에 의한 세포독성에 대한 세포 보호, 산화질소(nitric oxide) 생성 촉진, 콜라겐(collagen) 섬유 생성 억제, 혈관 두께 증가 억제 및 콜라겐 침착에 의한 섬유도 억제 활성과 같은 혈관 노화에 의한 증상 개선 효과를 나타내는 것을 확인함으로써, 혈관 노화로 유발되는 질환이나 증상의 예방, 치료 또는 개선용 조성물로서 유용하게 활용될 수 있다.
The present disclosure relates to a pharmaceutical composition for preventing or treating diseases caused by vascular aging, including a Salvia miltiorrhiza extract or a Paeonia lactiflora extract as an active ingredient, wherein it was found that a single extract of each of Salvia miltiorrhiza and Paeonia lactiflora or a mixed extract of both mixed in a specific weight ratio showed effects of improving symptoms by vascular aging such as cytoprotection against cytotoxicity due to vascular aging, promotion of nitric oxide production, inhibition of collagen fiber production, suppression of vascular thickness increase, and inhibitory activities on fibrosis by collagen deposition, thereby being useful as a composition for preventing, treating, or ameliorating diseases or symptoms caused by vascular aging.</description><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNj8Fqw0AMRH3JIbT5B0HPBeMmuYfSUuglNL2HyVpOBOtdI61Nku_KB3a3FHrNSTOa4SHNq9v2BO3heEzi4MnFfogmSWKgLioNyhOHJOFI2SVl_OpWjGFs5DAat3S40ARzo4cSjqVRQCpW5A5-ElAvPmNVT3IF8TkpXCrQLTiGnPvspfNR_1MYIVDZT0wZpdxKvuaxmnXwxou_-VA9vb99v3488xD3bEN-J3Daf341dbOs6_VqXTebl_taP4GJXwo</recordid><startdate>20240514</startdate><enddate>20240514</enddate><creator>SONG SUKJIN</creator><creator>CHA JINWOOK</creator><creator>BANG SANGWOO</creator><creator>SON JUAH</creator><creator>CHA MI RAN</creator><creator>OH BYULNIM</creator><scope>EVB</scope></search><sort><creationdate>20240514</creationdate><title>Pharmaceutical composition for preventing or treating diseases caused by vascular aging comprising Salvia miltiorrhiza extract or Paeonia lactiflora extract as an active ingredient</title><author>SONG SUKJIN ; CHA JINWOOK ; BANG SANGWOO ; SON JUAH ; CHA MI RAN ; OH BYULNIM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR20240065602A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2024</creationdate><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SONG SUKJIN</creatorcontrib><creatorcontrib>CHA JINWOOK</creatorcontrib><creatorcontrib>BANG SANGWOO</creatorcontrib><creatorcontrib>SON JUAH</creatorcontrib><creatorcontrib>CHA MI RAN</creatorcontrib><creatorcontrib>OH BYULNIM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SONG SUKJIN</au><au>CHA JINWOOK</au><au>BANG SANGWOO</au><au>SON JUAH</au><au>CHA MI RAN</au><au>OH BYULNIM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pharmaceutical composition for preventing or treating diseases caused by vascular aging comprising Salvia miltiorrhiza extract or Paeonia lactiflora extract as an active ingredient</title><date>2024-05-14</date><risdate>2024</risdate><abstract>본 발명은 단삼(Salvia miltiorrhiza) 또는 작약(Paeonialactiflora) 추출물을 유효성분으로 포함하는 혈관 노화로 유발되는 질환 예방 또는 치료용 약학 조성물에 관한 것으로, 단삼 및 작약 각각의 단독 추출물 또는 특정 중량비율로 혼합한 혼합 추출물이 혈관 노화에 의한 세포독성에 대한 세포 보호, 산화질소(nitric oxide) 생성 촉진, 콜라겐(collagen) 섬유 생성 억제, 혈관 두께 증가 억제 및 콜라겐 침착에 의한 섬유도 억제 활성과 같은 혈관 노화에 의한 증상 개선 효과를 나타내는 것을 확인함으로써, 혈관 노화로 유발되는 질환이나 증상의 예방, 치료 또는 개선용 조성물로서 유용하게 활용될 수 있다.
The present disclosure relates to a pharmaceutical composition for preventing or treating diseases caused by vascular aging, including a Salvia miltiorrhiza extract or a Paeonia lactiflora extract as an active ingredient, wherein it was found that a single extract of each of Salvia miltiorrhiza and Paeonia lactiflora or a mixed extract of both mixed in a specific weight ratio showed effects of improving symptoms by vascular aging such as cytoprotection against cytotoxicity due to vascular aging, promotion of nitric oxide production, inhibition of collagen fiber production, suppression of vascular thickness increase, and inhibitory activities on fibrosis by collagen deposition, thereby being useful as a composition for preventing, treating, or ameliorating diseases or symptoms caused by vascular aging.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Pharmaceutical composition for preventing or treating diseases caused by vascular aging comprising Salvia miltiorrhiza extract or Paeonia lactiflora extract as an active ingredient |
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